Query: 10 QVFIRSP---FPTRTLTLNPNQTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGKRLDEFT 69 QVF++SP P LT+NPNQT+ LK F S ++ T + FFSF+GK L + + Sbjct: 8 QVFVQSPEFQIPCHALTVNPNQTFHHLKLS---FISPTAPRETLDSLFFSFSGKPLLDSS 67
Query: 70 TVGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEKRLSKWT 129 T+ S I ST+ L +L GGGGDGG+T AESRDCYL MYA +KPDK DP+E RLS+WT Sbjct: 68 TLLDSKILPFSTLTLRTRLRGGGGDGGATGAESRDCYLKMYASKKPDKVDPNETRLSRWT 127
Query: 130 TCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPFSLYIKGLKDLIPIQLS--SG 189 TCALS EPLK PCV+DRLGNVFNK+ LV+ +L + LPK F +IKGLKD+IPI+LS G Sbjct: 128 TCALSFEPLKHPCVVDRLGNVFNKQPLVETLLERKLPKEFG-HIKGLKDMIPIELSPIPG 187
Query: 190 NEED---SSSSHFQCPISGFDFNGNYRFYALINCGHVLSAKALKQIKSSACLVCHKEFKE 249 + D S + FQCPI+G +FNG Y+F+AL +CGHVLSAKALK++KSS CLVCH+EF Sbjct: 188 VKYDDGISFMTRFQCPITGLEFNGKYKFFALRSCGHVLSAKALKEVKSSTCLVCHREF-S 247
Query: 250 EDDKIVINGTDEEVDILRKKMIQMKEMEKEKKAAIKLKKSKSKQLNSVGVAGEDDDGVIV 309 E DKIVINGT EEV LR++M +E+KA ++ KK K + +GV G +G + Sbjct: 248 ESDKIVINGTAEEVTALRERM-------EEEKAKLREKKEKKAKNGELGVNG--SEGGCL 307
Query: 310 GDAQLSGKKHGIDD--VVNANAKPEINPKLPNAIAVTKKA---SAKRFKAVDIAPANADK 369 ++LSG KH IDD V A+ K E N K+ NA K A S K+FKA DIAP NA K Sbjct: 308 DSSRLSGTKHAIDDRNVEKASVKLEGNGKIVNAGVTAKGATNGSVKKFKATDIAPPNATK 367
Query: 5 NSQNLQVFIRSPFPTRTLTLNPN-QTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGKRLD 64 N+++LQ+ + SP +L N +T +DLKN L F S S +F+FNGK L Sbjct: 2 NTKSLQILVHSPDLGISLQSTTNHETLSDLKNSL--FPQSHQSF------YFTFNGKPLP 61
Query: 65 EFTTVGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEKRLS 124 + T + S ST++L +LLGGGGDGG+T AESRDCYLNMYA++KPDK DP+E+RLS Sbjct: 62 DKTPL--SQFPPLSTLSLRSRLLGGGGDGGATGAESRDCYLNMYADKKPDKVDPNEQRLS 121
Query: 125 KWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPFSLYIKGLKDLIPIQLSS 184 KW CALSNEPL+ PCVID+LGN+FNKEALV+A+L K LPK F +IKGLKD+I +QLS+ Sbjct: 122 KWHNCALSNEPLREPCVIDKLGNIFNKEALVEALLGKKLPKEFG-HIKGLKDMINVQLSA 181
Query: 305 AQLSGKKHGID--DVVNANAKPEINPKLPN---AIAVTKKASAKRFKAVDIAPANADKKV 364 +LSG KHG+D V A+AK E N K+ N + A+AKRFKAVD+APANA K V Sbjct: 302 TRLSGTKHGVDGKGVEKASAKVERNGKVGNGNVGVNGGAAAAAKRFKAVDLAPANATKDV 361
Query: 6 SQNLQVFIRSP---FPTRTLTLNP--NQTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGK 65 ++ +Q+F+ SP PT+TLTL P +QT LK L F S SS +F+ NGK Sbjct: 5 ARRMQIFVESPDLQTPTKTLTLTPTKSQTLRSLKLFL--FPSEILSSC-----YFTLNGK 64
Query: 66 RLDEFTTVGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEK 125 RLD+ +++ SS IA ST+ L + GGGGDGG+T AESRDCYLNMYAE+KPDK DP+E+ Sbjct: 65 RLDDDSSILSSQIAPLSTLILRSRARGGGGDGGATGAESRDCYLNMYAEKKPDKVDPNEQ 124
Query: 126 RLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPFSLYIKGLKDLIPIQ 185 RLSKW CALSNEPLK PCV+D LGNVFNKEALV+A+L K++PK F ++KGLKD+I IQ Sbjct: 125 RLSKWLNCALSNEPLKEPCVVDWLGNVFNKEALVQALLGKNIPKAFG-HVKGLKDMIKIQ 184
Query: 246 VCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKKAAIKLKKSKSKQLNSVGVAG 305 VCH EF E DKIVING+DEEV +LR++M EMEK KLK+ K K++ + G Sbjct: 245 VCHVEF-SESDKIVINGSDEEVMVLRERM----EMEKG-----KLKEKKGKKVKNGG--- 304
Query: 306 EDDDGVIVGDAQLSGKKHGIDDVVNAN----AKPEINPKLPNA---IAVTKKAS-----A 365 DG+ A+LSG KHGI D V A+ +K E + K+ A + + K+S A Sbjct: 305 ---DGLDSDSARLSGTKHGIGDGVKADWKALSKVEADGKVGKAASNVRIPFKSSSNGNAA 364
Query: 6 SQNLQVFIRSP---FPTRTLTLNP--NQTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGK 65 ++ +Q+F+ SP PT+TLTL P +QT LK L F S SS +F+ NGK Sbjct: 5 ARRMQIFVESPDLQTPTKTLTLTPTKSQTLRSLKLFL--FPSEILSSC-----YFTLNGK 64
Query: 66 RLDEFTTVGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEK 125 RLD+ +++ SS IA ST+ L + GGGGDGG+T AESRDCYLNMYAE+KPDK DP+E+ Sbjct: 65 RLDDDSSILSSQIAPLSTLILRSRARGGGGDGGATGAESRDCYLNMYAEKKPDKVDPNEQ 124
Query: 126 RLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPFSLYIKGLKDLIPIQ 185 RLSKW CALSNEPLK PCV+D LGNVFNKEALV+A+L K++PK F ++KGLKD+I IQ Sbjct: 125 RLSKWLNCALSNEPLKEPCVVDWLGNVFNKEALVQALLGKNIPKAFG-HVKGLKDMIKIQ 184
Query: 246 VCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKKAAIKLKKSKSKQLNSVGVAG 305 VCH EF E DKIVING+DEEV +LR++M EMEK KLK+ K K++ + G Sbjct: 245 VCHVEF-SESDKIVINGSDEEVMVLRERM----EMEKG-----KLKEKKGKKVKNGG--- 304
Query: 306 EDDDGVIVGDAQLSGKKHGIDDVVNAN----AKPEINPKLPNA---IAVTKKAS-----A 365 DG+ A+LSG KHGI D V A+ +K E + K+ A + + K+S A Sbjct: 305 ---DGLDSDSARLSGTKHGIGDGVKADWKALSKVEADGKVGKAASNVRIPFKSSSNGNAA 364
Query: 5 NSQNLQVFIRSPFPTRTLTLNPN-QTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGKRLD 64 N+++LQ+ + SP +L N +T +DLKN L F S S +F+FNGK L Sbjct: 2 NTKSLQILVHSPDLGISLQSTTNHETLSDLKNSL--FPQSHQSF------YFTFNGKPLP 61
Query: 65 EFTTVGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEKRLS 124 + T + S ST++L +LLGGGGDGG+T AESRDCYLNMYA++KPDK DP+E+RLS Sbjct: 62 DKTPL--SQFPPLSTLSLRSRLLGGGGDGGATGAESRDCYLNMYADKKPDKVDPNEQRLS 121
Query: 125 KWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPFSLYIKGLKDLIPIQLSS 184 KW CALSNEPL+ PCVID+LGN+FNKEALV+A+L K LPK F +IKGLKD+I +QLS+ Sbjct: 122 KWHNCALSNEPLREPCVIDKLGNIFNKEALVEALLGKKLPKEFG-HIKGLKDMINVQLSA 181
Query: 305 AQLSGKKHGID--DVVNANAKPEINPKLPN---AIAVTKKASAKRFKAVDIAPANADKKV 364 +LSG KHG+D V A+AK E N K+ N + A+AKRFKAVD+APANA K V Sbjct: 302 TRLSGTKHGVDGKGVEKASAKVERNGKVGNGNVGVNGGAAAAAKRFKAVDLAPANATKDV 361
Query: 5 NSQNLQVFIRSP---FPTRTLTLNPNQTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGKR 64 ++++ Q+FI+S F T+TLTL+P QT L + + SS +F+ NGK Sbjct: 2 HTKSHQIFIQSQNPQFKTQTLTLDPTQTLTLYNLKLSLITDNQNPSSF----YFTLNGKP 61
Query: 65 LDEFTTVGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEKR 124 L + T + + I T+ L +L GGGGDGG+T AESRDCYLNMYA++KPDK DP E R Sbjct: 62 LKDSTCLPNPQITPLCTLILQVRLSGGGGDGGATGAESRDCYLNMYADKKPDKVDPHELR 121
Query: 125 LSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPFSLYIKGLKDLIPIQL 184 LSKW C+LSNEPL+ PCVIDRLGN+FNKEALV+A++ K LPK F YIKGLKD+I IQL Sbjct: 122 LSKWLNCSLSNEPLRQPCVIDRLGNMFNKEALVEALIGKKLPKEFG-YIKGLKDMIDIQL 181
Query: 185 SSGNEEDSSSSHFQCPISGFDFNGNYRFYALINCGHVLSAKALKQIKSSACLVCHKEFKE 244 + S ++ FQCP++G +FNG Y+F+AL NCGHVLSAKALK++KSS CLVC+KEF E Sbjct: 182 EVVPGDGSGNARFQCPVTGLEFNGKYKFFALKNCGHVLSAKALKEVKSSECLVCYKEF-E 241
Query: 245 EDDKIVINGTDEEVDILRKKMIQMKEMEKEKKAAIKLKKSKSKQLNSVGVAGEDDDGVIV 304 E DKIVING++EEV +LR++M +E+++ +K KK K + VG GE+ G Sbjct: 242 ECDKIVINGSEEEVAVLRERM-------EEERSKMKEKKMKKVKNGEVGANGEEFSGQGA 301
Query: 305 GDAQLSGKKHGIDDVVNAN---AKPEINPKLPNAIAVTKKASAKRFKAVDIAPANADKKV 364 +QLSGKKHGI DV + K + N K+ N V+ S KRFKA D+ P NA K+V Sbjct: 302 EVSQLSGKKHGIVDVKGVDKVVGKVKGNGKVENVKGVSHGGSVKRFKATDMVPTNATKEV 361
Query: 110 RKPDKGDPSEKRLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPF--- 169 +K +K D + +++W C LS E L+ P V LG ++NK+A+++ +L KS K Sbjct: 19 KKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKA 78
Query: 170 SLYIKGLKDLIPIQLS--------SGN-----EEDSSSSHFQCPISGFDFNGNYRFYALI 229 + +IK +K++ ++LS GN +D + F CP+ G + NG +RF L Sbjct: 79 ASHIKSIKNVTELKLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLR 138
Query: 230 NCGHVLSAKALKQIKSSACLVCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKK 289 CG V S +ALK+IK+ C C F +EDD IV+NGT+E+VD+L+ +M +E++ Sbjct: 139 CCGCVFSERALKEIKAEVCHTCGAAF-QEDDVIVLNGTNEDVDVLKARM-------EERR 198
Query: 290 AAIKLKKSKSKQLNSVGVAGEDDDGVIVGDAQLSGKKHGIDDVVNANAKPEINPKLPNAI 349 KL+K K + V+ D G +++ K G + + +++ + N P + Sbjct: 199 LRAKLEKKTKKPKAAESVSKPDVSEEAPGPSKV---KTGKPEETSLDSREKKNNLAPKSA 258
Query: 350 AVTKKASAKRFKAVDIAPANA-----DKKVYASLFTSSSRKSDFRE 375 A + S K K + A + + + Y SLFT+ S +E Sbjct: 259 ATNESFSGKAGKPLCGATKRSIADSEESEAYKSLFTTHSSAKRSKE 293
Query: 110 RKPDKGDPSEKRLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPF--- 169 +K +K D + +++W C LS E L+ P V LG ++NK+A+++ +L KS K Sbjct: 19 KKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKA 78
Query: 170 SLYIKGLKDLIPIQLS--------SGN-----EEDSSSSHFQCPISGFDFNGNYRFYALI 229 + +IK +K++ ++LS GN +D + F CP+ G + NG +RF L Sbjct: 79 ASHIKSIKNVTELKLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLR 138
Query: 230 NCGHVLSAKALKQIKSSACLVCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKK 289 CG V S +ALK+IK+ C C F +EDD IV+NGT E+VD+L+ +M +E++ Sbjct: 139 CCGCVFSERALKEIKAEVCHTCGAAF-QEDDVIVLNGTKEDVDVLKTRM-------EERR 198
Query: 290 AAIKLKKSKSKQLNSVGVAGEDDDGVIVGDAQLSGKKHGIDDVVNANAKPEINPKLPNAI 349 KL+K K + V+ D G +++ K G + + +++ + P + Sbjct: 199 LRAKLEKKTKKPKAAESVSKPDVSEEAPGPSKV---KTGKPEEASLDSREKKTNLAPKST 258
Query: 350 AVTKKASAKRFK----AVDIAPANADK-KVYASLFTSSSRKSDFRE 375 A + +S K K A + A++++ + Y SLFT+ S +E Sbjct: 259 ATNESSSGKAGKPPCGATKRSIADSEESEAYKSLFTTHSSAKRSKE 293
Query: 110 RKPDKGDPSEKRLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPF--- 169 +K +K D + +++W C LS E L+ P V LG ++NK+A+++ +L KS K Sbjct: 19 KKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKA 78
Query: 170 SLYIKGLKDLIPIQLS--------SGN-----EEDSSSSHFQCPISGFDFNGNYRFYALI 229 + +IK +K++ ++LS GN +D + F CP+ G + NG +RF L Sbjct: 79 ASHIKSIKNVTELKLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLR 138
Query: 230 NCGHVLSAKALKQIKSSACLVCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKK 289 CG V S +ALK+IK+ C C F +EDD I++NGT E+VD+L+ +M +E++ Sbjct: 139 CCGCVFSERALKEIKAEVCHTCGAAF-QEDDVIMLNGTKEDVDVLKTRM-------EERR 198
Query: 290 AAIKLKKSKSKQLNSVGVAGEDDDGVIVGDAQLSGKKHGIDDVVNANAKPEINPKLPNAI 349 KL+K K + V+ D G +++ K G + + +++ + P + Sbjct: 199 LRAKLEKKTKKPKAAESVSKPDVSEEAPGPSKV---KTGKPEEASLDSREKKTNLAPKST 258
Query: 350 AVTKKASAKRFK----AVDIAPANADK-KVYASLFTSSSRKSDFRE 375 A+ + +S K K A + A++++ + Y SLFT+ S +E Sbjct: 259 AMNESSSGKAGKPPCGATKRSIADSEESEAYKSLFTTHSSAKRSKE 293
Query: 110 RKPDKGDPSEKRLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPF--- 169 +K +K D + +++W C LS E L+ P V LG ++NK+A+++ +L KS K Sbjct: 19 KKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSAEKALGKA 78
Query: 170 SLYIKGLKDLIPIQLS--------SGN-----EEDSSSSHFQCPISGFDFNGNYRFYALI 229 + +I+ +K++ ++LS GN +D + F CP+ G + NG +RF L Sbjct: 79 ASHIRSIKNVTELRLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLR 138
Query: 230 NCGHVLSAKALKQIKSSACLVCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKK 289 CG V S +ALK+IK+ C C F+EE D IV+NGT E+V++L+K+M +E++ Sbjct: 139 CCGCVFSERALKEIKAEVCHTCGAAFQEE-DIIVLNGTKEDVEMLKKRM-------EERR 198
Query: 290 AAIKLKKSKSKQLNSVGVAGEDDDGVIVGDAQLSGKKHGIDDVVNANAKPEINPKLPNAI 349 KL+K K + A + G A S K G + + + + + + P Sbjct: 199 LRAKLEKKTKKPKTATECASK--PGTTQDSAGPSKVKSGKPEEADPDPREKKSTPAPRGA 258
Query: 350 AVTKKASAKRFK----AVDIAPANADK-KVYASLFTSSSRKSDFRE 375 A AS K K A+ + A++++ + Y S+FTS S +E Sbjct: 259 ATNGSASGKVGKPPCGALKRSIADSEESETYKSIFTSHSSAKRSKE 294
Query: 110 RKPDKGDPSEKRLSKWTTCALSNEPLKPPCVIDRLGNVFNKEALVKAMLAKSLPKPF--- 169 +K +K D + +++W C LS E L+ P V LG ++NK+A+++ +L KS K Sbjct: 19 KKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSSEKALGKA 78
Query: 170 SLYIKGLKDLIPIQLS--------SGN-----EEDSSSSHFQCPISGFDFNGNYRFYALI 229 + +IK +K++ ++LS GN +D + F CP+ G + NG +RF L Sbjct: 79 ASHIKSIKNVTELRLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLR 138
Query: 230 NCGHVLSAKALKQIKSSACLVCHKEFKEEDDKIVINGTDEEVDILRKKMIQMKEMEKEKK 289 CG V S +ALK+IK+ C C F +EDD IV+NGT E+V++L+ ++ +E++ Sbjct: 139 CCGCVFSERALKEIKAEVCHTCGAAF-QEDDVIVLNGTKEDVEVLKSRI-------EERR 198
Query: 290 AAIKLKKSKSKQLNSVGVAGEDDDGVIVGDAQLSGKKHGIDDVVNANAKPEINPKLPNAI 349 KL K K + V+ + G +++ K + K PK A Sbjct: 199 LRAKLGKKTKKPKVAESVSKSEVSEETPGPSKVKTGKPEETSLDTREKKTNSAPKSAAAH 258
Query: 350 AVTKKASAKRFKAVDIAPANADKKVYASLFTSSSRKSDFRE 375 +T +AKR A + + + Y SLFT+ S +E Sbjct: 259 GITSGKAAKRSIA-----DSEESEAYKSLFTTHSSAKRSKE 286
Query: 10 QVFIRSPFPTRT--LTLNPNQTWADLKNHLPFFNSSSSSSSTSEIGFFSFNGKRLDEFTT 69 Q+F++SP + L L+P Q+ L SS S ++ + +GK L+ T Sbjct: 6 QIFVKSPDCQKVVALQLDPAQSLLTLSGITSLLESSQRISFSA--CSITLDGKLLNGSTR 65
Query: 70 VGSSGIAQNSTVNLHFKLLGGGGDGGSTCAESRDCYLNMYAERKPDKGDPSEKRLSKWTT 129 + S + S + L +L GGGGDGG+T AESRDCYLNMYAE+KPDK DP+E+RLSKW Sbjct: 66 IQVSKLPSVSMLTLFPRLRGGGGDGGATGAESRDCYLNMYAEKKPDKVDPNEQRLSKWLN 125
Query: 250 DDKIVINGTDEEVDILRKKMIQMKEMEKEKKAAIKLKKSKSKQLNSVGVAGEDDDGVIVG 309 DKIVINGT+EEVD+LR++M +E+KA ++ KK SK+ + G A D G V Sbjct: 246 SDKIVINGTEEEVDLLRERM-------EEEKAKLREKKGVSKKSKN-GAAVVADTGAKVA 305
Query: 310 DAQLSGKKHGIDDVVNANAKPEINPKLPNAIAVTKKASAKRFKAVDIAPANADKKVYASL 369 Q+ D VN N + K+FKA D P NA K+VYASL Sbjct: 306 KRQIE------DGNVNGNG-----------------ITVKKFKAADKVPVNATKEVYASL 354
