Query: 14 ITTLSSTILILYLCFPTPLTATDGGDDTTEFDFGTLTLTSLKLLGDAHLNNGSVRLTRDL 73 IT + +L+L+ C T + T DTTEFDFGTLTL SLK++GDAHLNNGSV LTRDL Sbjct: 6 ITFTTVILLLLFCCSSTTTSTTTSDGDTTEFDFGTLTLASLKVIGDAHLNNGSVHLTRDL 65
Query: 254 TETHSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFG-TATVAVHAPPPSIAPS 313 TETHS++WWSF+SSF+S P P+ SPP VLP PTP G T VA APPPSIAPS Sbjct: 246 TETHSIEWWSFSSSFDSVVSSPVPQL--SPPVAVLPAPTPGAGGTNVVASRAPPPSIAPS 305
Query: 314 RSKSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRS 373 SKSM S S SC N+LCKHNPVAVAGVVTASAFLL I GGV+FW+FSKK+K K P + Sbjct: 306 GSKSM-SKESKSGSCDNQLCKHNPVAVAGVVTASAFLLVIFGGVIFWVFSKKSKFKFPPT 365
Query: 131 AASGGAGGFLGLSQ------GSNPGFVAVEFDTLMDVEFKDINGNHVGLDLGSMVSSHVS 190 G AGGF+GL + GS PGFVAVEFDTLMDVEFKDINGNHVGLDL SMVSS V Sbjct: 122 EIVGDAGGFMGLMRVDDSGSGSGPGFVAVEFDTLMDVEFKDINGNHVGLDLNSMVSSQVG 181
Query: 191 DLDSINIDLKSGDVINTWIEYSGLTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFV 250 DL + +IDLKSGD++N WIE+ G ++F+IS+SYSN+KP LLSF LD +V D M+V Sbjct: 182 DLAAADIDLKSGDLVNCWIEFDGSGRVFNISVSYSNLKPSDPLLSFPLDLDQYVNDFMYV 241
Query: 251 GFSGSTQGSTETHSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHA 310 GFSGSTQGSTE HSV+WWSF+SSF+ S+P P PP+ L PT +V + Sbjct: 242 GFSGSTQGSTEVHSVEWWSFSSSFD-STPSTGSAATPPPPTTTLMNPT------ANSVKS 301
Query: 311 PPPSIAPSRSKSMVST-----NGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFW 370 PPPS+ P+ S S ST N SSSC N+LCK P AVAGVVTA AF+LA+ GVL W Sbjct: 302 PPPSLPPTGSASASSTSTTQKNSKSSSCHNQLCKQGPGAVAGVVTAGAFVLALFAGVLIW 361
Query: 371 LFSKKTKLKLPRSSGGCSLTADIIKMPKEFSYKELKIATKGFDPGRIIGHGAFGTVYKGI 430 +++KK + S S +D+IKMPKEFSY+ELK ATK F+ R+IGHGAFG VYKGI Sbjct: 362 VYNKKIRHVKKSES---SFASDVIKMPKEFSYRELKAATKCFNANRVIGHGAFGIVYKGI 421
Query: 21 ILILYLCFPTPLTATDGGDDTTEFDFGTLTLTSLKLLGDAHLNNGSVRLTRDLPVPNSGA 80 + IL LC P T TEFDFGTLTL+SLKL+GDAHL+NGSVRLTRDL VPNSGA Sbjct: 8 LYILILCIPKXAVFTXVA--ATEFDFGTLTLSSLKLIGDAHLSNGSVRLTRDLAVPNSGA 67
Query: 81 GRVFYSHPVKFRQTGTNFPVSFTTYFSFTITNLNPSSIGGGLAFLISPDAAASGGAGGFL 140 GRV YS P++FRQ + P SF+T+FSF++TNLNPSSIGGGLAFLISPD A G AGGFL Sbjct: 68 GRVLYSKPIRFRQPSSPVPASFSTFFSFSVTNLNPSSIGGGLAFLISPDDVALGDAGGFL 127
Query: 201 INTWIEYSGLTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQGSTETHS 260 +N+WIEY G +Q+ ++S+SYSN+KPK +LSFS L +V D M+VGFSGSTQGSTE HS Sbjct: 188 VNSWIEYDGSSQVITVSVSYSNLKPKDPVLSFSLDLAQYVSDFMYVGFSGSTQGSTEIHS 247
Query: 261 VDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMV 320 V+WWSF+SSF+ S P P P PPS L PT +V +PPPS+ PS S S Sbjct: 248 VEWWSFSSSFD-SPVSPSGSPSPPPPSTTLMNPT------ANSVKSPPPSMPPSGSSSS- 307
Query: 321 STNGT-------SSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPR 380 + +GT SSSC N+LC+ P AVAGVVTASAF+LA+ GVL W++SKK K ++ + Sbjct: 308 NASGTNQKNSKSSSSCHNQLCREGPGAVAGVVTASAFVLALFAGVLIWVYSKKVK-QVKK 367
Query: 501 RMVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAFNARLGDFGLARQM 560 R L W HRRKIL GVASALAYLH+ECEN V+HRD+KTSNIMLDE FNARLGDFGLARQ+ Sbjct: 488 RTPLPWPHRRKILLGVASALAYLHQECENQVIHRDIKTSNIMLDEGFNARLGDFGLARQI 547
Query: 102 FTTYFSFTITNLNPSSIGGGLAFLISPDAAASGGAGGFLGLSQGSNPG--FVAVEFDTLM 161 F+T+FSF+ITNLNPSSIGGGLAF+I+PD A G AGGFLGL GS PG FVAVEFDTLM Sbjct: 87 FSTFFSFSITNLNPSSIGGGLAFVIAPDDAELGDAGGFLGLESGSAPGSGFVAVEFDTLM 146
Query: 162 DVEFKDINGNHVGLDLGSMVSSHVSDLDSINIDLKSGDVINTWIEYSGLTQIFSISISYS 221 DVEFKDIN NHVGLDL SMVS+ V DL SI++DLKSGD++N+WIEY G +++ ++S+SYS Sbjct: 147 DVEFKDINSNHVGLDLNSMVSTRVGDLSSIDVDLKSGDLVNSWIEYDGSSRVINVSVSYS 206
Query: 222 NVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQGSTETHSVDWWSFTSSFESS-SPEPEPE 281 N+KP+ +LS+S L +V D M+VGFSGSTQGSTE HSVDWWSF+SSF+S SP Sbjct: 207 NLKPRDPVLSYSLDLGQYVSDFMYVGFSGSTQGSTEIHSVDWWSFSSSFDSMLSPSGSSS 266
Query: 282 PEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMVSTNGT------SSSCGNELC 341 P P PP+ L PT +V +PPPS+ PS S +T+GT SSSC N LC Sbjct: 267 PPPPPPTTTLMNPT------ANSVKSPPPSMPPSGSSVSSNTSGTNQKNSKSSSCHNHLC 326
Query: 342 KHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGCSLTADIIKMPKEFSYK 401 + P AVAGVVTASAF+LA+ GV W++SK K K R S S +D+IKMPKEF+Y+ Sbjct: 327 REGPGAVAGVVTASAFVLALFAGVFIWVYSK--KFKHVRKSDN-SFASDVIKMPKEFTYR 386
Query: 14 ITTLSSTILILYLCFPTPLTATDGGDDTTEFDFGTLTLTSLKLLGDAHLNNGSVRLTRDL 73 IT + +L+L+ C T + T DTTEFDFGTLTL SLK++GDAHLNNGSV LTRDL Sbjct: 6 ITFTTVILLLLFCCSSTTTSTTTSDGDTTEFDFGTLTLASLKVIGDAHLNNGSVHLTRDL 65
Query: 254 TETHSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFG-TATVAVHAPPPSIAPS 313 TETHS++WWSF+SSF+S P P+ SPP VLP PTP G T VA APPPSIAPS Sbjct: 246 TETHSIEWWSFSSSFDSVVSSPVPQL--SPPVAVLPAPTPGAGGTNVVASRAPPPSIAPS 305
Query: 314 RSKSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRS 373 SKSM S S SC N+LCKHNPVAVAGVVTASAFLL I GGV+FW+FSKK+K K P + Sbjct: 306 GSKSM-SKESKSGSCDNQLCKHNPVAVAGVVTASAFLLVIFGGVIFWVFSKKSKFKFPPT 365
Query: 102 FTTYFSFTITNLNPSSIGGGLAFLISPDAAASGGAGGFLGLSQGSNPG--FVAVEFDTLM 161 F+T+FSF+ITNLNPSSIGGGLAFLI+PD A G AGGFLGL GS+PG FVAVEFDTLM Sbjct: 87 FSTFFSFSITNLNPSSIGGGLAFLIAPDDAELGDAGGFLGLESGSDPGSGFVAVEFDTLM 146
Query: 162 DVEFKDINGNHVGLDLGSMVSSHVSDLDSINIDLKSGDVINTWIEYSGLTQIFSISISYS 221 DVEFKDIN NHVGLDL SMVS+ V DL SI++DLKSGD++N+WIEY G +++ ++S+SYS Sbjct: 147 DVEFKDINSNHVGLDLNSMVSTRVGDLSSIDVDLKSGDLVNSWIEYDGSSRVINVSVSYS 206
Query: 222 NVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQGSTETHSVDWWSFTSSFESS-SPEPEPE 281 N+KP+ +LS+S L +V D M+VGFSGSTQGSTE HSVDWWSF+SSF+S SP Sbjct: 207 NLKPRDPVLSYSLDLGQYVSDFMYVGFSGSTQGSTEIHSVDWWSFSSSFDSMLSPSGSSS 266
Query: 282 PEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMVST---NGTSSSCGNELCKHN 341 P P PP+ L PT +V +PPPS+ PS S + ST N SSSC N LC+ Sbjct: 267 PPPPPPTTTLMNPT------ANSVKSPPPSMPPSGSSNTSSTNQKNSKSSSCRNHLCREG 326
Query: 342 PVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGCSLTADIIKMPKEFSYKELK 401 P AVAGVVTASAF+LA+ GV W++SK K K R S S +D+IKMPKEF+Y+ELK Sbjct: 327 PGAVAGVVTASAFVLALFAGVFIWVYSK--KFKNVRKSDN-SFASDVIKMPKEFTYRELK 386
Query: 203 DVINTWIEYSGLTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQGSTET 262 D++N W+EY G TQ+F+IS+SYSN+KPK+ LLSF LD +V D MFVGFSGSTQGSTE Sbjct: 191 DLVNVWVEYDGSTQLFNISVSYSNLKPKEPLLSFDLDLDQYVNDFMFVGFSGSTQGSTEI 250
Query: 263 HSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKS 322 H+++WWSF+SSF+ S P P P ++++ P TA + PPPS+APS S S Sbjct: 251 HNIEWWSFSSSFDVVSATGSSSPPP-PTASLMNP------TANSVIPPPPPSMAPSASDS 310
Query: 323 MVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGC 382 VS SSC N+LCK P AVAGVVTA AFL+ + GVL W+FSKK K + +S Sbjct: 311 -VSHTAKPSSCHNQLCKQGPGAVAGVVTAGAFLV-LFAGVLIWVFSKKFK-HVKKSE--- 370
Query: 17 LSSTILILYLCFPTPLTATDGGDDTTEFDFGTLTLTSLKLLGDAHLNNGSVRLTRDLPVP 76 L+S L L C A TEFDFGTLTL SLKLLGDAH+NNGSVRLTRD+ VP Sbjct: 9 LTSLNLSLVFCLFVINNAVITISTATEFDFGTLTLASLKLLGDAHMNNGSVRLTRDVTVP 68
Query: 77 NSGAGRVFYSHPVKFRQTGTNFPVSFTTYFSFTITNLNPSSIGGGLAFLISPDAAASGGA 136 GAG+ YS PV+FR GT+ P SF+T+FSF+ITNLNPSSIG GLAF+I+PD G A Sbjct: 69 YDGAGKALYSKPVRFRLPGTHTPASFSTFFSFSITNLNPSSIGAGLAFVITPDGEQVGSA 128
Query: 257 ETHSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRS 316 E HS++WWSF+SSFES+S P P ++++ P TA +V +PPPS+APS S Sbjct: 249 EIHSIEWWSFSSSFESNSGTGSGSAPPPPTASLMNP------TAN-SVKSPPPSLAPSGS 308
Query: 317 KSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSG 376 S + SSSC N+LCK AVAGVVTASAF AI GVL W FSK+ K + +S Sbjct: 309 -STTQKSSKSSSCHNQLCKQGAGAVAGVVTASAFF-AIFAGVLIWFFSKRYK-HVKKSE- 368
Query: 377 GCSLTADIIKMPKEFSYKELKIATKGFDPGRIIGHGAFGTVYKGILAETGLVVAVKRCSH 436 S T+DII+MPKEFSY+EL+ ATK F+ RIIGHGAFGTVYKGIL + G ++AVKRCSH Sbjct: 369 --SFTSDIIRMPKEFSYRELRSATKCFNANRIIGHGAFGTVYKGILPQNGDIIAVKRCSH 428
Query: 259 HSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPP-SIAPSRSK 318 HS++WWSF+SSF SS P P +N++ P +V +PPP + PS S Sbjct: 246 HSIEWWSFSSSFGSSLGSGSGSPPPR--ANLMNPKAN-------SVKSPPPLASQPSSSA 305
Query: 319 SMVSTN-----GTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLP 378 +S+N +SSSC + CK NP +AGVVTA AF LA+ G LFW++SKK K ++ Sbjct: 306 IPISSNTQLKTSSSSSCHSRFCKENPGTIAGVVTAGAFFLALFAGALFWVYSKKFK-RVE 365
Query: 499 SRMVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAFNARLGDFGLARQ 558 SR L W HR+KIL GVASALAYLH ECEN V+HRDVK+SNIMLDE+FNA+LGDFGLARQ Sbjct: 486 SRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDESFNAKLGDFGLARQ 545
Query: 559 MEHDKSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASGRRPIEKEKNGIK 618 +EHDKSP+ATVAAGTMGYLAPEYLLTGRA++KTDVFSYGAV LEV SGRRPIEK+ N + Sbjct: 546 IEHDKSPEATVAAGTMGYLAPEYLLTGRASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQR 605
Query: 619 ---GIG-NLVEWVWGLHTEGRLLEGVDERLNGEYDEMEMRRVLFVGLACSHPDPNERPTM 678 G+ NLVEWVWGL+ EG++ D RL G++DE EM RVL VGLACSHPDP RPTM Sbjct: 606 HNVGVNPNLVEWVWGLYKEGKVSAAADSRLEGKFDEGEMWRVLVVGLACSHPDPAFRPTM 665
Query: 21 ILILYLCFPTPLTATDGGDDTTEFDFGTLTLTSLKLLGDAHLNNGSVRLTRDLPVPNSGA 80 IL +LC + G T FD GTLTL+SLKLLGDAHLNNG+++LTR+L VP S A Sbjct: 18 ILASFLCS----SDVRGDFPATRFDLGTLTLSSLKLLGDAHLNNGTIKLTRELSVPTSTA 77
Query: 81 GRVFYSHPVKFRQTGTNFPVSFTTYFSFTITNLNPSSIGGGLAFLISPDAAASGGAGGFL 140 G+ Y PVKFR T P SFTTYFSF++TNLNPSSIGGGLAF+ISPD G GGFL Sbjct: 78 GKALYGKPVKFRHPETKSPASFTTYFSFSVTNLNPSSIGGGLAFVISPDEDYLGSTGGFL 137
Query: 201 INTWIEYSGLTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQGSTETHS 260 +N+WI Y G ++ ++ +SYSN+KPK +LS LD +V D MFVGFSGSTQGSTE HS Sbjct: 198 VNSWITYDGSGRVLTVYVSYSNLKPKSPILSVPLDLDRYVSDSMFVGFSGSTQGSTEIHS 257
Query: 261 VDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMV 320 VDWWSF+SSFE SS P P P PPS+ P SI PS S Sbjct: 258 VDWWSFSSSFEESSESPPPMPNSPPPSS------------------PSSSITPSLSTVRR 317
Query: 321 STNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGCSL 380 T SSSC N+LCK +P AVAGVVTA AF LA+ GV+ W++SKK +K R S SL Sbjct: 318 KTADPSSSCRNKLCKKSPAAVAGVVTAGAFFLALFAGVIIWVYSKK--IKYTRKSE--SL 377
Query: 441 QGKNEFLSELSIIGTLRHRNLVRLQGWCHEKEEILLVYDLMPNGSLDKALFESRMVLSWA 500 QG EFLSELS+IGTLRHRNL+RLQG+C EK EILL+YDLMPNGSLDKAL+ES L W Sbjct: 438 QGNTEFLSELSLIGTLRHRNLLRLQGYCREKGEILLIYDLMPNGSLDKALYESPTTLPWP 497
Query: 561 ATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASGRRPI---EKEKNGIKGI-GN 620 AT AAGTMGYLAPEYLLTGRAT+KTDVFSYGAV LEV +GRRPI E E G+ + Sbjct: 558 ATAAAGTMGYLAPEYLLTGRATEKTDVFSYGAVVLEVCTGRRPITRPEPEPGLRPGLRSS 617
Query: 311 PSRSKSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGV--------LFWLFS 370 P RSKS N + SS N+ +PV + LAI G+ ++F Sbjct: 271 PVRSKSNHLHNVSDSSVVND----DPVVIPSKKRRHRHNLAIGLGISCPVLICLALFVFG 330
Query: 371 KKTKLKLPRSSGGCSLTADIIKMPKEFSYKELKIATKGFDPGRIIGHGAFGTVYKGILAE 430 T K L ++I +EFSYKEL ATKGF R+IG GAFG VY+ + Sbjct: 331 YFTLKKWKSVKAEKELKTELITGLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVS 390
Query: 431 TGLVVAVKRCSHKNGGQGKNEFLSELSIIGTLRHRNLVRLQGWCHEKEEILLVYDLMPNG 490 +G + AVKR H N +GK EFL+ELSII LRH+NLV+LQGWC+EK E+LLVY+ MPNG Sbjct: 391 SGTISAVKRSRH-NSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPNG 450
Query: 491 SLDKALFESR----MVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAF 550 SLDK L++ + L W+HR I G+ASAL+YLH ECE VVHRD+KTSNIMLD F Sbjct: 451 SLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLDINF 510
Query: 551 NARLGDFGLARQMEHDKSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASG 610 NARLGDFGLAR EHDKSP +T+ AGTMGYLAPEYL G AT+KTD FSYG V LEVA G Sbjct: 511 NARLGDFGLARLTEHDKSPVSTLTAGTMGYLAPEYLQYGTATEKTDAFSYGVVILEVACG 570
Query: 671 DPNERPTMRCVVQMLVGETEVPIVPRTKPSMSFTTSQLLLSLQDSVSD 707 D NERP+MR V+Q+L E E VP+ KP++SF+ LSL D VS+ Sbjct: 631 DSNERPSMRRVLQILNNEIEPSPVPKMKPTLSFSCG---LSLDDIVSE 669
Query: 65 GSVRLTRDLPVPNSGAGRVFYSHPVKFRQTGTNFPVSFTTYFSFTITNLNPSSIGGGLAF 124 G++RLT + G FYS P++F+ G N +SF+T F+ + + G GLAF Sbjct: 50 GAIRLTTET---QRVIGHAFYSLPIRFKPIGVNRALSFSTSFAIAMVPEFVTLGGHGLAF 109
Query: 125 LISPDAAASGGAGG-FLGLSQGSNPGF----VAVEFDTLMDVEFKDINGNHVGLDLGSMV 184 I+P G +LGL S F AVEFDT+ D+EF+DIN NHVG+D+ SM Sbjct: 110 AITPTPDLRGSLPSQYLGLLNSSRVNFSSHFFAVEFDTVRDLEFEDINDNHVGIDINSME 169
Query: 185 SS-------HVSDLDSINIDLKSGDVINTWIEYSGLTQIFSISISYSNVKPKQSLLSFSF 244 SS +++ + L G VI WI+Y + + +S + KPK SLLS+ Sbjct: 170 SSISTPAGYFLANSTKKELFLDGGRVIQAWIDYDSNKKRLDVKLSPFSEKPKLSLLSYDV 229
Query: 245 VLDDFVGDEMFVGFSGSTQGSTETHSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPT 304 L +GDEM+VGFS ST +H + W+F S E+ Sbjct: 230 DLSSVLGDEMYVGFSASTGLLASSHYILGWNFNMSGEA---------------------- 289
Query: 305 PPFGTATVAVHAPPPSIAPSRSKSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAI 364 F + ++ P SI + K G S C + A +V AS F++ Sbjct: 290 --FSLSLPSLPRIPSSIKKRKKKRQSLILGVSLLCS-------LLIFAVLVAASLFVV-- 349
Query: 365 LGGVLFWLFSKKTKLKLPRSSGGCSLTADIIKMPKEFSYKELKIATKGFDPGRIIGHGAF 424 K+K L P FSY+ELK AT GF ++G G F Sbjct: 350 ------------RKVKDEDRVEEWELDFG----PHRFSYRELKKATNGFGDKELLGSGGF 409
Query: 425 GTVYKGILAETGLVVAVKRCSHKNGGQGKNEFLSELSIIGTLRHRNLVRLQGWCHEKEEI 484 G VYKG L + VAVKR SH++ QG EF+SE+S IG LRHRNLV+L GWC ++++ Sbjct: 410 GKVYKGKLPGSDEFVAVKRISHES-RQGVREFMSEVSSIGHLRHRNLVQLLGWCRRRDDL 469
Query: 485 LLVYDLMPNGSLDKALFES--RMVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTS 544 LLVYD MPNGSLD LF+ ++L+W R KI+ GVAS L YLHE E V+HRD+K + Sbjct: 470 LLVYDFMPNGSLDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAA 529
Query: 545 NIMLDEAFNARLGDFGLARQMEHDKSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGA 604 N++LD N R+GDFGLA+ EH P AT GT GYLAPE +G+ T TDV+++GA Sbjct: 530 NVLLDSEMNGRVGDFGLAKLYEHGSDPGATRVVGTFGYLAPELTKSGKLTTSTDVYAFGA 589
Query: 45 DFGTLT------LTSLKLLGDAHLNNGSVRLTRDLPV-----------PNSGAGRVFYSH 104 DF TL+ L +L L GDA + ++ LT+ P +SG GR Y + Sbjct: 20 DFPTLSHRFSPPLQNLTLYGDAFFRDRTISLTQQQPCFPSVTTPPSKPSSSGIGRALYVY 79
Query: 165 PGFVAVEFDTLMDVEFKDINGNHVGLDLGSMVSSHVSDLDSINIDLKSGDVINTWIEYSG 224 F+AVEFDT D DIN NHVG+D+ S+ S D S DLKSG + WIEYS Sbjct: 140 -SFIAVEFDTRFDPVHGDINDNHVGIDVSSIFSVSSVDAISKGFDLKSGKKMMAWIEYSD 199
Query: 225 LTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQG-STETHSVDWWSFTS 284 + ++ + + YS VKP +LS L V + M VGFS S G + H V+ W F + Sbjct: 200 VLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGIGSALHIVERWKFRT 259
Query: 285 SFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMVSTNGTSSS 344 S E E E V + V P I V+ G Sbjct: 260 FGSHSDAIQEEEEEKDEECLV----------CSGEVSENPKEIHRKGFNFRVTVVGLK-- 319
Query: 345 CGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGCSLTADIIKMP 404 + V ++ A ++ ++ ++F L K ++ S + +++MP Sbjct: 320 ----------IPVWSLLPGLAAIVILVAFIVFSLICGKKRISEEADSN-----SGLVRMP 379
Query: 405 KEFSYKELKIATKGFDPGRIIGHGAFGTVYKGILAETGLVVAVKRCSHKNGGQ-GKNEFL 464 S E+K AT GF+ I+G GA TVY+G + G V AVKR ++ Q +N F Sbjct: 380 GRLSLAEIKSATSGFNENAIVGQGASATVYRGSIPSIGSV-AVKRFDREHWPQCNRNPFT 439
Query: 465 SELSII-GTLRHRNLVRLQGWCHEKEEILLVYDLMPNGSLDKALF--------ESRMVLS 524 +E + + G LRH+NLV+ QGWC E E LV++ +PNGSL + L E +VLS Sbjct: 440 TEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLS 499
Query: 525 WAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAFNARLGDFGLARQMEHD-- 584 W R I+ GVASAL YLHEECE ++HRDVKT NIMLD FNA+LGDFGLA EH Sbjct: 500 WKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSAL 559
Query: 585 -KSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASGRRPIEKEKNGIKGIG 644 AT+ AGTMGYLAPEY+ TG ++KTDV+S+G V LEV +GRRP+ G G Sbjct: 560 LAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPV-----GDDG-A 619
Query: 645 NLVEWVWGLHTEGRLLEGVDERLNGEYDEMEMRRVLFVGLACSHPDPNERPTMRCVVQML 688 LV+ +W G++L+G D L E+D EM RVL VG+ C+HPD +RP ++ V+++ Sbjct: 620 VLVDLMWSHWETGKVLDGADIMLREEFDAEEMERVLMVGMVCAHPDSEKRPRVKDAVRII 658
Query: 259 HSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPP-SIAPSRSK 318 HS++WWSF+SSF SS P P +N++ P +V +PPP + PS S Sbjct: 246 HSIEWWSFSSSFGSSLGSGSGSPPPR--ANLMNPKAN-------SVKSPPPLASQPSSSA 305
Query: 319 SMVSTN-----GTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLP 378 +S+N +SSSC + CK NP +AGVVTA AF LA+ G LFW++SKK K ++ Sbjct: 306 IPISSNTQLKTSSSSSCHSRFCKENPGTIAGVVTAGAFFLALFAGALFWVYSKKFK-RVE 365
Query: 499 SRMVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAFNARLGDFGLARQ 558 SR L W HR+KIL GVASALAYLH ECEN V+HRDVK+SNIMLDE+FNA+LGDFGLARQ Sbjct: 486 SRFTLPWDHRKKILLGVASALAYLHRECENQVIHRDVKSSNIMLDESFNAKLGDFGLARQ 545
Query: 559 MEHDKSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASGRRPIEKEKNGIK 618 +EHDKSP+ATVAAGTMGYLAPEYLLTGRA++KTDVFSYGAV LEV SGRRPIEK+ N + Sbjct: 546 IEHDKSPEATVAAGTMGYLAPEYLLTGRASEKTDVFSYGAVVLEVVSGRRPIEKDLNVQR 605
Query: 619 ---GIG-NLVEWVWGLHTEGRLLEGVDERLNGEYDEMEMRRVLFVGLACSHPDPNERPTM 678 G+ NLVEWVWGL+ EG++ D RL G++DE EM RVL VGLACSHPDP RPTM Sbjct: 606 HNVGVNPNLVEWVWGLYKEGKVSAAADSRLEGKFDEGEMWRVLVVGLACSHPDPAFRPTM 665
Query: 21 ILILYLCFPTPLTATDGGDDTTEFDFGTLTLTSLKLLGDAHLNNGSVRLTRDLPVPNSGA 80 IL +LC + G T FD GTLTL+SLKLLGDAHLNNG+++LTR+L VP S A Sbjct: 18 ILASFLCS----SDVRGDFPATRFDLGTLTLSSLKLLGDAHLNNGTIKLTRELSVPTSTA 77
Query: 81 GRVFYSHPVKFRQTGTNFPVSFTTYFSFTITNLNPSSIGGGLAFLISPDAAASGGAGGFL 140 G+ Y PVKFR T P SFTTYFSF++TNLNPSSIGGGLAF+ISPD G GGFL Sbjct: 78 GKALYGKPVKFRHPETKSPASFTTYFSFSVTNLNPSSIGGGLAFVISPDEDYLGSTGGFL 137
Query: 201 INTWIEYSGLTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQGSTETHS 260 +N+WI Y G ++ ++ +SYSN+KPK +LS LD +V D MFVGFSGSTQGSTE HS Sbjct: 198 VNSWITYDGSGRVLTVYVSYSNLKPKSPILSVPLDLDRYVSDSMFVGFSGSTQGSTEIHS 257
Query: 261 VDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMV 320 VDWWSF+SSFE SS P P P PPS+ P SI PS S Sbjct: 258 VDWWSFSSSFEESSESPPPMPNSPPPSS------------------PSSSITPSLSTVRR 317
Query: 321 STNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGCSL 380 T SSSC N+LCK +P AVAGVVTA AF LA+ GV+ W++SKK +K R S SL Sbjct: 318 KTADPSSSCRNKLCKKSPAAVAGVVTAGAFFLALFAGVIIWVYSKK--IKYTRKSE--SL 377
Query: 441 QGKNEFLSELSIIGTLRHRNLVRLQGWCHEKEEILLVYDLMPNGSLDKALFESRMVLSWA 500 QG EFLSELS+IGTLRHRNL+RLQG+C EK EILL+YDLMPNGSLDKAL+ES L W Sbjct: 438 QGNTEFLSELSLIGTLRHRNLLRLQGYCREKGEILLIYDLMPNGSLDKALYESPTTLPWP 497
Query: 561 ATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASGRRPI---EKEKNGIKGI-GN 620 AT AAGTMGYLAPEYLLTGRAT+KTDVFSYGAV LEV +GRRPI E E G+ + Sbjct: 558 ATAAAGTMGYLAPEYLLTGRATEKTDVFSYGAVVLEVCTGRRPITRPEPEPGLRPGLRSS 617
Query: 311 PSRSKSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAILGGV--------LFWLFS 370 P RSKS N + SS N+ +PV + LAI G+ ++F Sbjct: 271 PVRSKSNHLHNVSDSSVVND----DPVVIPSKKRRHRHNLAIGLGISCPVLICLALFVFG 330
Query: 371 KKTKLKLPRSSGGCSLTADIIKMPKEFSYKELKIATKGFDPGRIIGHGAFGTVYKGILAE 430 T K L ++I +EFSYKEL ATKGF R+IG GAFG VY+ + Sbjct: 331 YFTLKKWKSVKAEKELKTELITGLREFSYKELYTATKGFHSSRVIGRGAFGNVYRAMFVS 390
Query: 431 TGLVVAVKRCSHKNGGQGKNEFLSELSIIGTLRHRNLVRLQGWCHEKEEILLVYDLMPNG 490 +G + AVKR H N +GK EFL+ELSII LRH+NLV+LQGWC+EK E+LLVY+ MPNG Sbjct: 391 SGTISAVKRSRH-NSTEGKTEFLAELSIIACLRHKNLVQLQGWCNEKGELLLVYEFMPNG 450
Query: 491 SLDKALFESR----MVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAF 550 SLDK L++ + L W+HR I G+ASAL+YLH ECE VVHRD+KTSNIMLD F Sbjct: 451 SLDKILYQESQTGAVALDWSHRLNIAIGLASALSYLHHECEQQVVHRDIKTSNIMLDINF 510
Query: 551 NARLGDFGLARQMEHDKSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASG 610 NARLGDFGLAR EHDKSP +T+ AGTMGYLAPEYL G AT+KTD FSYG V LEVA G Sbjct: 511 NARLGDFGLARLTEHDKSPVSTLTAGTMGYLAPEYLQYGTATEKTDAFSYGVVILEVACG 570
Query: 671 DPNERPTMRCVVQMLVGETEVPIVPRTKPSMSFTTSQLLLSLQDSVSD 707 D NERP+MR V+Q+L E E VP+ KP++SF+ LSL D VS+ Sbjct: 631 DSNERPSMRRVLQILNNEIEPSPVPKMKPTLSFSCG---LSLDDIVSE 669
Query: 65 GSVRLTRDLPVPNSGAGRVFYSHPVKFRQTGTNFPVSFTTYFSFTITNLNPSSIGGGLAF 124 G++RLT + G FYS P++F+ G N +SF+T F+ + + G GLAF Sbjct: 50 GAIRLTTET---QRVIGHAFYSLPIRFKPIGVNRALSFSTSFAIAMVPEFVTLGGHGLAF 109
Query: 125 LISPDAAASGGAGG-FLGLSQGSNPGF----VAVEFDTLMDVEFKDINGNHVGLDLGSMV 184 I+P G +LGL S F AVEFDT+ D+EF+DIN NHVG+D+ SM Sbjct: 110 AITPTPDLRGSLPSQYLGLLNSSRVNFSSHFFAVEFDTVRDLEFEDINDNHVGIDINSME 169
Query: 185 SS-------HVSDLDSINIDLKSGDVINTWIEYSGLTQIFSISISYSNVKPKQSLLSFSF 244 SS +++ + L G VI WI+Y + + +S + KPK SLLS+ Sbjct: 170 SSISTPAGYFLANSTKKELFLDGGRVIQAWIDYDSNKKRLDVKLSPFSEKPKLSLLSYDV 229
Query: 245 VLDDFVGDEMFVGFSGSTQGSTETHSVDWWSFTSSFESSSPEPEPEPEPSPPSNVLPPPT 304 L +GDEM+VGFS ST +H + W+F S E+ Sbjct: 230 DLSSVLGDEMYVGFSASTGLLASSHYILGWNFNMSGEA---------------------- 289
Query: 305 PPFGTATVAVHAPPPSIAPSRSKSMVSTNGTSSSCGNELCKHNPVAVAGVVTASAFLLAI 364 F + ++ P SI + K G S C + A +V AS F++ Sbjct: 290 --FSLSLPSLPRIPSSIKKRKKKRQSLILGVSLLCS-------LLIFAVLVAASLFVV-- 349
Query: 365 LGGVLFWLFSKKTKLKLPRSSGGCSLTADIIKMPKEFSYKELKIATKGFDPGRIIGHGAF 424 K+K L P FSY+ELK AT GF ++G G F Sbjct: 350 ------------RKVKDEDRVEEWELDFG----PHRFSYRELKKATNGFGDKELLGSGGF 409
Query: 425 GTVYKGILAETGLVVAVKRCSHKNGGQGKNEFLSELSIIGTLRHRNLVRLQGWCHEKEEI 484 G VYKG L + VAVKR SH++ QG EF+SE+S IG LRHRNLV+L GWC ++++ Sbjct: 410 GKVYKGKLPGSDEFVAVKRISHES-RQGVREFMSEVSSIGHLRHRNLVQLLGWCRRRDDL 469
Query: 485 LLVYDLMPNGSLDKALFES--RMVLSWAHRRKILHGVASALAYLHEECENLVVHRDVKTS 544 LLVYD MPNGSLD LF+ ++L+W R KI+ GVAS L YLHE E V+HRD+K + Sbjct: 470 LLVYDFMPNGSLDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAA 529
Query: 545 NIMLDEAFNARLGDFGLARQMEHDKSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGA 604 N++LD N R+GDFGLA+ EH P AT GT GYLAPE +G+ T TDV+++GA Sbjct: 530 NVLLDSEMNGRVGDFGLAKLYEHGSDPGATRVVGTFGYLAPELTKSGKLTTSTDVYAFGA 589
Query: 45 DFGTLT------LTSLKLLGDAHLNNGSVRLTRDLPV-----------PNSGAGRVFYSH 104 DF TL+ L +L L GDA + ++ LT+ P +SG GR Y + Sbjct: 20 DFPTLSHRFSPPLQNLTLYGDAFFRDRTISLTQQQPCFPSVTTPPSKPSSSGIGRALYVY 79
Query: 165 PGFVAVEFDTLMDVEFKDINGNHVGLDLGSMVSSHVSDLDSINIDLKSGDVINTWIEYSG 224 F+AVEFDT D DIN NHVG+D+ S+ S D S DLKSG + WIEYS Sbjct: 140 -SFIAVEFDTRFDPVHGDINDNHVGIDVSSIFSVSSVDAISKGFDLKSGKKMMAWIEYSD 199
Query: 225 LTQIFSISISYSNVKPKQSLLSFSFVLDDFVGDEMFVGFSGSTQG-STETHSVDWWSFTS 284 + ++ + + YS VKP +LS L V + M VGFS S G + H V+ W F + Sbjct: 200 VLKLIRVWVGYSRVKPTSPVLSTQIDLSGKVKEYMHVGFSASNAGIGSALHIVERWKFRT 259
Query: 285 SFESSSPEPEPEPEPSPPSNVLPPPTPPFGTATVAVHAPPPSIAPSRSKSMVSTNGTSSS 344 S E E E V + V P I V+ G Sbjct: 260 FGSHSDAIQEEEEEKDEECLV----------CSGEVSENPKEIHRKGFNFRVTVVGLK-- 319
Query: 345 CGNELCKHNPVAVAGVVTASAFLLAILGGVLFWLFSKKTKLKLPRSSGGCSLTADIIKMP 404 + V ++ A ++ ++ ++F L K ++ S + +++MP Sbjct: 320 ----------IPVWSLLPGLAAIVILVAFIVFSLICGKKRISEEADSN-----SGLVRMP 379
Query: 405 KEFSYKELKIATKGFDPGRIIGHGAFGTVYKGILAETGLVVAVKRCSHKNGGQ-GKNEFL 464 S E+K AT GF+ I+G GA TVY+G + G V AVKR ++ Q +N F Sbjct: 380 GRLSLAEIKSATSGFNENAIVGQGASATVYRGSIPSIGSV-AVKRFDREHWPQCNRNPFT 439
Query: 465 SELSII-GTLRHRNLVRLQGWCHEKEEILLVYDLMPNGSLDKALF--------ESRMVLS 524 +E + + G LRH+NLV+ QGWC E E LV++ +PNGSL + L E +VLS Sbjct: 440 TEFTTMTGYLRHKNLVQFQGWCSEGTETALVFEYLPNGSLSEFLHKKPSSDPSEEIIVLS 499
Query: 525 WAHRRKILHGVASALAYLHEECENLVVHRDVKTSNIMLDEAFNARLGDFGLARQMEHD-- 584 W R I+ GVASAL YLHEECE ++HRDVKT NIMLD FNA+LGDFGLA EH Sbjct: 500 WKQRVNIILGVASALTYLHEECERQIIHRDVKTCNIMLDAEFNAKLGDFGLAEIYEHSAL 559
Query: 585 -KSPDATVAAGTMGYLAPEYLLTGRATDKTDVFSYGAVALEVASGRRPIEKEKNGIKGIG 644 AT+ AGTMGYLAPEY+ TG ++KTDV+S+G V LEV +GRRP+ G G Sbjct: 560 LAGRAATLPAGTMGYLAPEYVYTGVPSEKTDVYSFGVVVLEVCTGRRPV-----GDDG-A 619
Query: 645 NLVEWVWGLHTEGRLLEGVDERLNGEYDEMEMRRVLFVGLACSHPDPNERPTMRCVVQML 688 LV+ +W G++L+G D L E+D EM RVL VG+ C+HPD +RP ++ V+++ Sbjct: 620 VLVDLMWSHWETGKVLDGADIMLREEFDAEEMERVLMVGMVCAHPDSEKRPRVKDAVRII 658
The following BLAST results are available for this feature:
