Query: 41 MGFQSFYLSCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSGKALSYWNS---QSYCNYTG 100 M F+ F S FI+ LS LNS+Q+TSN+QSQYFTLMK SLSG ALSYW+ SYCNYTG Sbjct: 1 MAFRFFCFSSFILCLSFLNSLQATSNKQSQYFTLMKKSLSGHALSYWSGNGGNSYCNYTG 60
Query: 101 VTCNIQNQVTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEV 160 +TCNIQ QVTK+NISGW +KGSLP +CSYLPELRVLD SNN+ G PDGIINCS LEV Sbjct: 61 ITCNIQGQVTKLNISGWLVKGSLPPYVCSYLPELRVLDTSNNTFPGPVPDGIINCSLLEV 120
Query: 41 MGFQSFYLSCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSGKALSYWNS---QSYCNYTG 100 M F +L ++F + S ++ + QSQ+F L K S+SG +LS W S SYCNYTG Sbjct: 4 MAFHRLFLFLLLVFSANYISCRANISSQSQFFDLFKKSVSGNSLSNWASGKGNSYCNYTG 63
Query: 101 VTCNIQNQVTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEV 160 + C+ Q V +++ISGWSL G P +CSYLP LRVL + NN+ G+FP GIINCSFLE Sbjct: 64 IACDDQENVVQIDISGWSLSGRFPEEICSYLPGLRVLRLRNNNFIGSFPLGIINCSFLEE 123
Query: 161 LNMSSLNLSGKLPNFSRMKSLRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSNLNRWE 220 L++SS+ L+G LP+FS +KSLR LDLSYN F G+FPMSI NLTN+EV+NFNEN + N WE Sbjct: 124 LSLSSIYLTGPLPDFSPLKSLRILDLSYNRFSGNFPMSITNLTNLEVLNFNENGDFNLWE 183
Query: 221 LPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLK 280 LPENITRLT++++++L+T L+G I P++GNM+SL+DLELSGNYL G +P ELG L+NL+ Sbjct: 184 LPENITRLTKLKSMILTTCMLRGEIPPALGNMTSLIDLELSGNYLVGRVPKELGLLRNLQ 243
Query: 281 SLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYNNSLTGE 340 L LYYN+L G IP ELGNLTEL DLDMSVNK GRIP+SICRLPKL LQ+YNN+L GE Sbjct: 244 ELELYYNQLEGEIPTELGNLTELRDLDMSVNKFIGRIPESICRLPKLVVLQLYNNTLEGE 303
Query: 941 VICMAIRCTARAPVPRPTMNEIVQFLGEIEPCRFVSCKSTNNTKHTLNPTTINKTFQL 996 V+ +A+RCT R PV RPTMNE+VQ L E +PC+F CK +N TK T NPT F L Sbjct: 904 VLRVAVRCTCRTPVLRPTMNEVVQLLIEADPCKFDCCKLSNKTKETANPTKPKNQFDL 961
Query: 61 VQSTSNQQSQYFTLMKNSLSGKALSYWN---SQSYCNYTGVTCNIQNQVTKVNISGWSLK 120 +Q++S QSQ+F LMK SLSG L W ++S+CN+TGV+CN Q V K++++GWS+ Sbjct: 1 MQASSMNQSQFFNLMKTSLSGNVLFDWEVTGAKSFCNFTGVSCNSQGYVEKLDMTGWSIS 60
Query: 121 GSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSSLNLSGKLPNFSRMKS 180 G P +CSYLPELRVL +S+N + G FP IINCS LE LNMS+L LSG LP+FS +KS Sbjct: 61 GRFPEGICSYLPELRVLRLSHNQLHGGFPHSIINCSLLEELNMSTLYLSGILPDFSPLKS 120
Query: 181 LRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTK 240 LR LD+SYN F GDFPMS+ NLTN+E++NFNEN N W+LPENI+RLT++++++L T Sbjct: 121 LRKLDMSYNSFRGDFPMSVTNLTNLELLNFNENVEFNLWQLPENISRLTKLKSMILMTCM 180
Query: 241 LQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLKSLMLYYN-ELTGTIPEELGN 300 L G I SIGNM SL+DLELSGN+L G IP E+G LKNL+ L LYYN L+G IPEELGN Sbjct: 181 LYGPIPASIGNMISLIDLELSGNFLSGPIPVEIGLLKNLQQLELYYNYHLSGNIPEELGN 240
Query: 361 FLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAK 420 LTGEVP+NLG+ S M +LDLSEN+L+G LP ++C GGKL YFLVL NMF+GE+P+++AK Sbjct: 301 ILTGEVPQNLGQLSAMLVLDLSENRLSGPLPAEVCKGGKLFYFLVLDNMFSGELPDSYAK 360
Query: 421 CTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSN 480 C +L+RFRVS+N+L+G +P+GL LPHV++IDL++N F G I IG A+NLSE QSN Sbjct: 361 CKTLLRFRVSHNRLEGPIPEGLLSLPHVSIIDLSYNNFRGSIPNTIGTARNLSELFLQSN 420
Query: 481 KLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNKLNSSIPDSLSE 540 K+SG LPPEISGA++LVK+D+SNNLLSGP+P +IG L KLN+L+L+ N LNSSI SLS Sbjct: 421 KISGVLPPEISGAINLVKIDVSNNLLSGPVPFQIGFLMKLNVLMLQGNMLNSSITKSLSL 480
Query: 61 VQSTSNQQSQYFTLMKNSLSGKALSYWN---SQSYCNYTGVTCNIQNQVTKVNISGWSLK 120 +Q++S QSQ+F LMK SLSG L W ++S+CN+TGV+CN Q V K++++GWS+ Sbjct: 1 MQASSMNQSQFFNLMKTSLSGNVLFDWEVTGAKSFCNFTGVSCNSQGYVEKLDMTGWSIS 60
Query: 121 GSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSSLNLSGKLPNFSRMKS 180 G P +CSYLPELRVL +S+N + G FP IINCS LE LNMS+L LSG LP+FS +KS Sbjct: 61 GRFPEGICSYLPELRVLRLSHNQLHGGFPHSIINCSLLEELNMSTLYLSGILPDFSPLKS 120
Query: 181 LRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTK 240 LR LD+SYN F GDFPMS+ NLTN+E++NFNEN N W+LPENI+RLT++++++L T Sbjct: 121 LRKLDMSYNSFRGDFPMSVTNLTNLELLNFNENVEFNLWQLPENISRLTKLKSMILMTCM 180
Query: 241 LQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLKSLMLYYN-ELTGTIPEELGN 300 L G I SIGNM SL+DLELSGN+L G IP E+G LKNL+ L LYYN L+G IPEELGN Sbjct: 181 LYGPIPASIGNMISLIDLELSGNFLSGPIPVEIGLLKNLQQLELYYNYHLSGNIPEELGN 240
Query: 361 FLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAK 420 LTGEVP+NLG+ S M +LDLSEN+L+G LP ++C GGKL YFLVL NMF+GE+P+++AK Sbjct: 301 ILTGEVPQNLGQLSAMLVLDLSENRLSGPLPAEVCKGGKLFYFLVLDNMFSGELPDSYAK 360
Query: 421 CTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSN 480 C +L+RFRVS+N+L+G +P+GL LPHV++IDL++N F G I IG A+NLSE QSN Sbjct: 361 CKTLLRFRVSHNRLEGPIPEGLLSLPHVSIIDLSYNNFRGSIPNTIGTARNLSELFLQSN 420
Query: 481 KLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNKLNSSIPDSLSE 540 K+SG LPPEISGA++LVK+D+SNNLLSGP+P +IG L KLN+L+L+ N LNSSI SLS Sbjct: 421 KISGVLPPEISGAINLVKIDVSNNLLSGPVPFQIGFLMKLNVLMLQGNMLNSSITKSLSL 480
Query: 61 VQSTSNQQSQYFTLMKNSLSGKALSYWN---SQSYCNYTGVTCNIQNQVTKVNISGWSLK 120 +Q++S QSQ+F LMK SLSG L W ++S+CN+TGV+CN Q V K++++GWS+ Sbjct: 1 MQASSMNQSQFFNLMKTSLSGNVLFDWEVTGAKSFCNFTGVSCNSQGYVEKLDMTGWSIS 60
Query: 121 GSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSSLNLSGKLPNFSRMKS 180 G P +CSYLPELRVL +S+N + G FP IINCS LE LNMS+L LSG LP+FS +KS Sbjct: 61 GRFPEGICSYLPELRVLRLSHNQLHGGFPHSIINCSLLEELNMSTLYLSGILPDFSPLKS 120
Query: 181 LRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTK 240 LR LD+SYN F GDFPMS+ NLTN+E++NFNEN N W+LPENI+RLT++++++L T Sbjct: 121 LRKLDMSYNSFRGDFPMSVTNLTNLELLNFNENVEFNLWQLPENISRLTKLKSMILMTCM 180
Query: 241 LQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLKSLMLYYN-ELTGTIPEELGN 300 L G I SIGNM SL+DLELSGN+L G IP E+G LKNL+ L LYYN L+G IPEELGN Sbjct: 181 LYGPIPASIGNMISLIDLELSGNFLSGPIPVEIGLLKNLQQLELYYNYHLSGNIPEELGN 240
Query: 361 FLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAK 420 LTGEVP+NLG+ S M +LDLSEN+L+G LP ++C GGKL YFLVL NMF+GE+P+++AK Sbjct: 301 ILTGEVPQNLGQLSAMLVLDLSENRLSGPLPAEVCKGGKLFYFLVLDNMFSGELPDSYAK 360
Query: 421 CTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSN 480 C +L+RFRVS+N+L+G +P+GL LPHV++IDL++N F G I IG A+NLSE QSN Sbjct: 361 CKTLLRFRVSHNRLEGPIPEGLLSLPHVSIIDLSYNNFRGSIPNTIGTARNLSELFLQSN 420
Query: 481 KLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNKLNSSIPDSLSE 540 K+SG LPPEISGA++LVK+D+SNNLLSGP+P +IG L KLN+L+L+ N LNSSI SLS Sbjct: 421 KISGVLPPEISGAINLVKIDVSNNLLSGPVPFQIGFLMKLNVLMLQGNMLNSSITKSLSL 480
Query: 46 FYLSCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSGKALSYWN---SQSYCNYTGVTCNI 105 F FI +SL + +++ S QSQ+F L+K SLSG ALS W+ +SYCN+TGV+CN Sbjct: 5 FIFFLFISLISLAHPLEAISTNQSQFFNLLKTSLSGNALSDWDVSGGKSYCNFTGVSCNS 64
Query: 106 QNQVTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSS 165 Q V K +I+GWS+ G P +CSYLP+LRV+ + +N + G F IINCSFLE LN+S Sbjct: 65 QGYVEKFDITGWSISGRFPDGMCSYLPQLRVIRLGHNHLHGNFLPSIINCSFLEELNVSL 124
Query: 166 LNLSGKLPNFSRMKSLRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSNLNRWELPENI 225 L L GK+P+FS +KSLR LD+SYN F DFPMS+ NLTN+E +NFNEN+ LN WELPENI Sbjct: 125 LYLDGKIPDFSPLKSLRMLDMSYNNFRDDFPMSVTNLTNLEFLNFNENAELNYWELPENI 184
Query: 226 TRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLKSLMLY 285 +RLT++++++L+T L G I +IGNM+SL+DLELSGN+L G IP E+G LKNLK L LY Sbjct: 185 SRLTKLKSMILTTCNLYGPIPATIGNMTSLIDLELSGNFLTGQIPPEIGLLKNLKQLELY 244
Query: 286 YN-ELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYNNSLTGEIPSV 345 YN L+G+IPEELGNLTEL DLDMSVNKLTG IP SICRLPKL LQ YNNSLTGEIPS Sbjct: 245 YNYHLSGSIPEELGNLTELVDLDMSVNKLTGNIPASICRLPKLEVLQFYNNSLTGEIPSA 304
Query: 346 LGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLVYFLV 405 + S TL LS+Y N LTGE+P NLG+ S M +LD+SEN+L+G LP ++C+GGKL+YFLV Sbjct: 305 IAESTTLRILSLYDNSLTGELPHNLGQLSGMVVLDVSENRLSGPLPTEVCSGGKLLYFLV 364
Query: 406 LSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGKISPL 465 L NMF+G +P ++AKC +L+RFRVS+N+L+GS+P+GL GLPHV++IDL +N F+G IS Sbjct: 365 LDNMFSGGLPSSYAKCKTLLRFRVSHNRLEGSIPEGLLGLPHVSIIDLGYNNFSGSISNT 424
Query: 466 IGYAKNLSEFLAQSNKLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLL 525 I A+NLSE QSNK+SG LPPEISGA++LVK+D+SNNLLSGP+P +IG L KLNLL+L Sbjct: 425 IRTARNLSELFLQSNKISGVLPPEISGAINLVKIDVSNNLLSGPVPFQIGYLTKLNLLML 484
Query: 526 RNNKLNSSIPDSLSELKSLNLLDLSSNLLTGNLPHSLSELIPNSVNFSNNHLYGPIPLSL 585 + N LNSSIPDSLS LKSLN+LDLS+NLLTGN+P SLS L+PNS++FSNN L GPIPL L Sbjct: 485 QGNMLNSSIPDSLSFLKSLNVLDLSNNLLTGNVPESLSVLLPNSIDFSNNRLSGPIPLPL 544
Query: 586 IKEGLEDSFLENPGLCVTTYTYSSDRSFPLCRQTCTRKRLNLMWVVVASVFLLLVGAILF 645 IK GL +SF NPGLCV Y S D++FP+C + RKRLN +WV+ SV + +VGA+ F Sbjct: 545 IKGGLLESFSGNPGLCVPIYVVS-DQNFPVCSRRYNRKRLNSIWVIGISVVIFIVGALFF 604
Query: 646 LKQWSRKGKSLIGNDETMSSSLCSYDVKSFHRISFNQREILEAMVDKNIVGHGGSGTVYR 705 LK+ K K L G DETMSSS SY+VKSFHRISF+Q+EILE M++KN VG GGSGTVY+ Sbjct: 605 LKRKLSKDK-LTGRDETMSSSFFSYEVKSFHRISFDQQEILEGMIEKNKVGQGGSGTVYK 664
Query: 706 IGLSNGEIVAVKKLWSRKTKDKVSEDQVFPDKELETEVETLGNIRHKNIVKLYCYLSSLD 765 I LS+GE++AVK+LWS++ KD EDQ+ PDK L+TEVETLG+IRHKNIVKLYCY SS Sbjct: 665 IELSSGEVIAVKRLWSKRNKDSAIEDQLLPDKGLKTEVETLGSIRHKNIVKLYCYFSSFH 724
Query: 766 CSLLVYEYMPNGNLWDALHKEKMLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDIKSS 825 CSLLVYEYMPNGNL DAL K + LDWPTRHQIALGVAQGLAYLHHDLL I+HRDIKS+ Sbjct: 725 CSLLVYEYMPNGNLRDALDKNWIHLDWPTRHQIALGVAQGLAYLHHDLLTPIIHRDIKST 784
Query: 946 AIRCTARAPVPRPTMNEIVQFLGEIEPCRFVSCKSTNNTKHTLNPTTINKTFQL 996 AIRC + P PRPTMNE+VQ L E +PCRF SCKS+N K T N T IN +L Sbjct: 905 AIRCICKTPAPRPTMNEVVQLLIEADPCRFDSCKSSNKAKETSNVTKINSKNEL 956
Query: 51 FIIFLSLLNSVQSTSNQQSQYFTLMKNSLSG--KALSYWNSQ--SYCNYTGVTCNIQ-NQ 110 +++FL LL + NQ +K SL LS WNS S C ++GV+C + Sbjct: 2 YLLFLFLLFPTVFSLNQDGFILQQVKLSLDDPDSYLSSWNSNDASPCRWSGVSCAGDFSS 61
Query: 111 VTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSSLNL 170 VT V++S +L G PS +C L L L + NNSI T P I C L+ L++S L Sbjct: 62 VTSVDLSSANLAGPFPSVICR-LSNLAHLSLYNNSINSTLPLNIAACKSLQTLDLSQNLL 121
Query: 171 SGKLP-------------------------NFSRMKSLRALDLSYNLFDGDFPMSIMNLT 230 +G+LP +F + ++L L L YNL DG P + N++ Sbjct: 122 TGELPQTLADIPTLVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIS 181
Query: 231 NIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGN 290 ++++N + N + +P LT + + L+ L G I S+G +S LVDL+L+ N Sbjct: 182 TLKMLNLSYNP-FSPSRIPPEFGNLTNLEVMWLTECHLVGQIPDSLGQLSKLVDLDLALN 241
Query: 291 YLRGWIPHELGRLKNLKSLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICR 350 L G IP LG L N+ + LY N LTG IP ELGNL L LD S+N+LTG+IPD +CR Sbjct: 242 DLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLKSLRLLDASMNQLTGKIPDELCR 301
Query: 351 LPKLRGLQIYNNSLTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSEN 410 +P L L +Y N+L GE+P+ + S L + I+ N LTG +PK+LG +S + LD+SEN Sbjct: 302 VP-LESLNLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSPLRWLDVSEN 361
Query: 411 KLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFG 470 + +G LP +C G+L L++ N F+G IPE+ A C SL R R++ N+ GSVP G +G Sbjct: 362 EFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADCRSLTRIRLAYNRFSGSVPTGFWG 421
Query: 471 LPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSNKLSGALPPEISGAVSLVKVDLSNN 530 LPHV +++L N F+G+IS IG A NLS + +N+ +G+LP EI +L ++ S N Sbjct: 422 LPHVNLLELVNNSFSGEISKSIGGASNLSLLILSNNEFTGSLPEEIGSLDNLNQLSASGN 481
Query: 531 LLSGPIPS------EIGNL------------------KKLNLLLLRNNKLNSSIPDSLSE 590 SG +P E+G L KKLN L L +N+ IPD + Sbjct: 482 KFSGSLPDSLMSLGELGTLDLHGNQFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGS 541
Query: 591 LKSLNLLDLSSNLLTGNLPHSLSELIPNSVNFSNNHLYGPIPLSLIKEGLEDSFLENPGL 650 L LN LDLS N+ +G +P SL L N +N S N L G +P SL K+ ++SF+ NPGL Sbjct: 542 LSVLNYLDLSGNMFSGKIPVSLQSLKLNQLNLSYNRLSGDLPPSLAKDMYKNSFIGNPGL 601
Query: 651 CVTTYTYSSDRSFPLCRQTCTRKRLNLMWVVVASVFLLLVGAILFLKQWSRKGKSLIGND 710 C LC K+ +W ++ S+F+L +L W Sbjct: 602 CGDIK--------GLCGSENEAKKRGYVW-LLRSIFVLAAMVLLAGVAWFYFKYRTFKKA 661
Query: 711 ETMSSSLCSYDVKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGLSNGEIVAVKKLW 770 M S + + SFH++ F++ EILE++ + N++G G SG VY++ L+NGE VAVK+LW Sbjct: 662 RAMERS--KWTLMSFHKLGFSEHEILESLDEDNVIGAGASGKVYKVVLTNGETVAVKRLW 721
Query: 771 S---RKTKDKVSEDQVFP---DKELETEVETLGNIRHKNIVKLYCYLSSLDCSLLVYEYM 830 + ++T D E P D+ E EVETLG IRHKNIVKL+C S+ DC LLVYEYM Sbjct: 722 TGSVKETGDCDPEKGYKPGVQDEAFEAEVETLGKIRHKNIVKLWCCCSTRDCKLLVYEYM 781
Query: 831 PNGNLWDALHKEK-MLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDIKSSNILLDVDF 890 PNG+L D LH K +L W TR +I L A+GL+YLHHD +P IVHRDIKS+NIL+D D+ Sbjct: 782 PNGSLGDLLHSSKGGMLGWQTRFKIILDAAEGLSYLHHDSVPPIVHRDIKSNNILIDGDY 841
Query: 891 QPKVADFGVAKVLQAMSGNESSNTVIAGTYGYMDPDYANTSKATTKCDVYSFGVVLMELV 950 +VADFGVAK + S +VIAG+ GY+ P+YA T + K D+YSFGVV++E+V Sbjct: 842 GARVADFGVAKAVDLTGKAPKSMSVIAGSCGYIAPEYAYTLRVNEKSDIYSFGVVILEIV 901
Query: 951 TGKKPVEAEFGENKNIINWVSTKVETKQGAMEVLDKHVSGSFRDDMLQVICMAIRCTARA 967 T K+PV+ E GE K+++ WV + ++ K G V+D + F++++ +++ + + CT+ Sbjct: 902 TRKRPVDPELGE-KDLVKWVCSTLDQK-GIEHVIDPKLDSCFKEEISKILNVGLLCTSPL 961
Query: 48 LSCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSG-----KALSYW---NSQSYCNYTGVT 107 L C I+ L L +S S +Q T+++ + G ++LS W N + C + GV+ Sbjct: 2 LYCLILLLCL-SSTYLPSLSLNQDATILRQAKLGLSDPAQSLSSWSDNNDVTPCKWLGVS 61
Query: 108 CNIQNQVTKVNISGWSLKGSLPSNLC------------------------SYLPELRVLD 167 C+ + V V++S + L G PS LC L LD Sbjct: 62 CDATSNVVSVDLSSFMLVGPFPSILCHLPSLHSLSLYNNSINGSLSADDFDTCHNLISLD 121
Query: 168 ISNNSIQGTFPDGI-INCSFLEVLNMSSLNLSGKLPN-FSRMKSLRALDLSYNLFDGDFP 227 +S N + G+ P + N L+ L +S NLS +P+ F + L +L+L+ N G P Sbjct: 122 LSENLLVGSIPKSLPFNLPNLKFLEISGNNLSDTIPSSFGEFRKLESLNLAGNFLSGTIP 181
Query: 228 MSIMNLTNIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLV 287 S+ N+T ++ + N + ++P + LT ++ L L+ L G I PS+ ++SLV Sbjct: 182 ASLGNVTTLKELKLAYNL-FSPSQIPSQLGNLTELQVLWLAGCNLVGPIPPSLSRLTSLV 241
Query: 288 DLELSGNYLRGWIPHELGRLKNLKSLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGR 347 +L+L+ N L G IP + +LK ++ + L+ N +G +PE +GN+T L D S+NKLTG+ Sbjct: 242 NLDLTFNQLTGSIPSWITQLKTVEQIELFNNSFSGELPESMGNMTTLKRFDASMNKLTGK 301
Query: 348 IPDSICRLPKLRGLQIYNNSLTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMT 407 IPD++ L L L ++ N L G +P + S TLS L +++N LTG +P LG +S + Sbjct: 302 IPDNL-NLLNLESLNLFENMLEGPLPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQ 361
Query: 408 LLDLSENKLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGS 467 +DLS N+ +G++P +C GKL Y +++ N F+GEI KC SL R R+SNN+L G Sbjct: 362 YVDLSYNRFSGEIPANVCGEGKLEYLILIDNSFSGEISNNLGKCKSLTRVRLSNNKLSGQ 421
Query: 468 VPQGLFGLPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSNKLSGALPPEI------- 527 +P G +GLP +++++L+ N FTG I I AKNLS N+ SG++P EI Sbjct: 422 IPHGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNEIGSLNGII 481
Query: 528 --SGAVS---------------LVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNKLNSS 587 SGA + L ++DLS N LSG IP E+ K LN L L NN L+ Sbjct: 482 EISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELRGWKNLNELNLANNHLSGE 541
Query: 588 IPDSLSELKSLNLLDLSSNLLTGNLPHSLSELIPNSVNFSNNHLYGPIPLSLIKEGLEDS 647 IP + L LN LDLSSN +G +P L L N +N S NHL G IP + Sbjct: 542 IPKEVGILPVLNYLDLSSNQFSGEIPLELQNLKLNVLNLSYNHLSGKIPPLYANKIYAHD 601
Query: 708 WSRKGKSLIGNDETMSSSLCSYDVKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGL 767 RK ++L SS+L + +SFH++ F++ EI + + +KN++G G SG VY++ L Sbjct: 662 -CRKLRAL------KSSTLAASKWRSFHKLHFSEHEIADCLDEKNVIGFGSSGKVYKVEL 721
Query: 768 SNGEIVAVKKLWSRKTK---DKVSEDQVFPDKELETEVETLGNIRHKNIVKLYCYLSSLD 827 GE+VAVKKL ++ K D+ S D + D EVETLG IRHK+IV+L+C SS D Sbjct: 722 RGGEVVAVKKL-NKSVKGGDDEYSSDSLNRD-VFAAEVETLGTIRHKSIVRLWCCCSSGD 781
Query: 828 CSLLVYEYMPNGNLWDALHKEK---MLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDI 887 C LLVYEYMPNG+L D LH ++ ++L WP R +IAL A+GL+YLHHD +P IVHRD+ Sbjct: 782 CKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDV 841
Query: 888 KSSNILLDVDFQPKVADFGVAKVLQAMSGNESSNTV--IAGTYGYMDPDYANTSKATTKC 947 KSSNILLD D+ KVADFG+AKV Q MSG+++ + IAG+ GY+ P+Y T + K Sbjct: 842 KSSNILLDSDYGAKVADFGIAKVGQ-MSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKS 901
Query: 948 DVYSFGVVLMELVTGKKPVEAEFGENKNIINWVSTKVETKQGAMEVLDKHVSGSFRDDML 984 D+YSFGVVL+ELVTGK+P ++E G+ K++ WV T ++ K G V+D + F++++ Sbjct: 902 DIYSFGVVLLELVTGKQPTDSELGD-KDMAKWVCTALD-KCGLEPVIDPKLDLKFKEEIS 961
Query: 52 IIFLSLLNSVQSTSNQQSQYFTLMKNSL----SGKALSYWNSQ-SYCNYTGVTCNIQNQV 111 ++FL L S +S +++ + +K++ S W + S C + G+ CN V Sbjct: 10 LLFLMPLASSRSNHSEEVENLLKLKSTFGETKSDDVFKTWTHRNSACEFAGIVCNSDGNV 69
Query: 112 TKVNISGWSLKG--------SLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVL 171 ++N+ SL LP + L L L + NNS++G + C+ L L Sbjct: 70 VEINLGSRSLINRDDDGRFTDLPFDSICDLKLLEKLVLGNNSLRGQIGTNLGKCNRLRYL 129
Query: 172 NMSSLNLSGKLPNFSRMKSLRALDLSYNLFDGDFPMS-IMNLTNIEVVNFNENSNLNRWE 231 ++ N SG+ P ++ L L L+ + G FP S + +L + ++ +N Sbjct: 130 DLGINNFSGEFPAIDSLQLLEFLSLNASGISGIFPWSSLKDLKRLSFLSVGDN-RFGSHP 189
Query: 232 LPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLK 291 P I LT ++ + LS + + G I I N+ L +LELS N + G IP E+ +LKNL+ Sbjct: 190 FPREILNLTALQWVYLSNSSITGKIPEGIKNLVRLQNLELSDNQISGEIPKEIVQLKNLR 249
Query: 292 SLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYNNSLTGE 351 L +Y N+LTG +P NLT L + D S N L G + + + L L L ++ N LTGE Sbjct: 250 QLEIYSNDLTGKLPLGFRNLTNLRNFDASNNSLEGDLSE-LRFLKNLVSLGMFENRLTGE 309
Query: 352 IPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLV 411 IP G+ +L+ LS+Y N LTG++P+ LG + +D+SEN L G++PP +C G + Sbjct: 310 IPKEFGDFKSLAALSLYRNQLTGKLPRRLGSWTAFKYIDVSENFLEGQIPPYMCKKGVMT 369
Query: 412 YFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGK 471 + L+L N FTG+ PE++AKC +L+R RVSNN L G +P G++GLP++ +DLA N F G Sbjct: 370 HLLMLQNRFTGQFPESYAKCKTLIRLRVSNNSLSGMIPSGIWGLPNLQFLDLASNYFEGN 429
Query: 532 LLLL------------------------RNNKLNSSIPDSLSELKSLNLLDLSSNLLTGN 591 L+L N L+ IP+SL LK LN L+LS N L+G Sbjct: 490 SLILDQNNLSGAIPKSLGLCTSLVDLNFAGNSLSEEIPESLGSLKLLNSLNLSGNKLSGM 549
Query: 592 LPHSLSELIPNSVNFSNNHLYGPIPLSLIKEGLEDSFLENPGLCVTTYTYSSDRSFPLCR 651 +P LS L + ++ SNN L G +P SL+ SF N GLC + Y R PL + Sbjct: 550 IPVGLSALKLSLLDLSNNQLTGSVPESLV----SGSFEGNSGLCSSKIRYL--RPCPLGK 609
Query: 652 QTCTRKRLNL----MWVVVASVFLL--LVGAILFLKQWSRKGKSLIGNDETMSSSLCSYD 711 KR +L M +VA++ L L ++F + + K++ ++ + Sbjct: 610 PHSQGKRKHLSKVDMCFIVAAILALFFLFSYVIFKIRRDKLNKTVQKKND--------WQ 669
Query: 712 VKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGLSNGEIVAVKKLWSRKTKDKV--S 771 V SF ++FN+ EI++ + +NI+G GG G VY++ L +GE +AVK +W ++ + S Sbjct: 670 VSSFRLLNFNEMEIIDEIKSENIIGRGGQGNVYKVSLRSGETLAVKHIWCPESSHESFRS 729
Query: 772 EDQVFPD-------KELETEVETLGNIRHKNIVKLYCYLSSLDCSLLVYEYMPNGNLWDA 831 + D E E EV TL NI+H N+VKL+C ++ D LLVYEYMPNG+LW+ Sbjct: 730 STAMLSDGNNRSNNGEFEAEVATLSNIKHINVVKLFCSITCEDSKLLVYEYMPNGSLWEQ 789
Query: 832 LHKEK--MLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDIKSSNILLDVDFQPKVADF 891 LH+ + + W R +ALG A+GL YLHH L ++HRD+KSSNILLD +++P++ADF Sbjct: 790 LHERRGEQEIGWRVRQALALGAAKGLEYLHHGLDRPVIHRDVKSSNILLDEEWRPRIADF 849
Query: 892 GVAKVLQAMS-GNESSNTVIAGTYGYMDPDYANTSKATTKCDVYSFGVVLMELVTGKKPV 951 G+AK++QA S + S ++ GT GY+ P+YA T+K K DVYSFGVVLMELVTGKKP+ Sbjct: 850 GLAKIIQADSVQRDFSAPLVKGTLGYIAPEYAYTTKVNEKSDVYSFGVVLMELVTGKKPL 909
Query: 175 LEVLNMSSLNLSGKLP-NFSRMKSLRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSNL 234 L LN S NLSG L + + SL LDL N F G P S NL + + + N+ Sbjct: 151 LVHLNASGNNLSGNLTEDLGNLVSLEVLDLRGNFFQGSLPSSFKNLQKLRFLGLSGNNLT 210
Query: 235 NRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRL 294 ELP + +L + T +L + +G I P GN++SL L+L+ L G IP ELG+L Sbjct: 211 G--ELPSVLGQLPSLETAILGYNEFKGPIPPEFGNINSLKYLDLAIGKLSGEIPSELGKL 270
Query: 295 KNLKSLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYNNS 354 K+L++L+LY N TGTIP E+G++T L LD S N LTG IP I +L L+ L + N Sbjct: 271 KSLETLLLYENNFTGTIPREIGSITTLKVLDFSDNALTGEIPMEITKLKNLQLLNLMRNK 330
Query: 355 LTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNG 414 L+G IP + + L L +++N L+GE+P +LGK+S + LD+S N +G++P +CN Sbjct: 331 LSGSIPPAISSLAQLQVLELWNNTLSGELPSDLGKNSPLQWLDVSSNSFSGEIPSTLCNK 390
Query: 415 GKLVYFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQ 474 G L ++ +N FTG+IP T + C SLVR R+ NN L GS+P G L + ++LA N+ Sbjct: 391 GNLTKLILFNNTFTGQIPATLSTCQSLVRVRMQNNLLNGSIPIGFGKLEKLQRLELAGNR 450
Query: 475 FTGKIS---------PLIGYAKN---------------LSEFLAQSNKLSGALPPEISGA 534 +G I I +++N L FL N +SG +P + Sbjct: 451 LSGGIPGDISDSVSLSFIDFSRNQIRSSLPSTILSIHNLQAFLVADNFISGEVPDQFQDC 510
Query: 535 VSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNKLNSSIPDSLSELKSLNLLDLSSNL 594 SL +DLS+N L+G IPS I + +KL L LRNN L IP ++ + +L +LDLS+N Sbjct: 511 PSLSNLDLSSNTLTGTIPSSIASCEKLVSLNLRNNNLTGEIPRQITTMSALAVLDLSNNS 570
Query: 595 LTGNLPHSL-SELIPNSVNFSNNHLYGPIPLS-LIKEGLEDSFLENPGLCVTTY-TYSSD 654 LTG LP S+ + +N S N L GP+P++ +K D N GLC S Sbjct: 571 LTGVLPESIGTSPALELLNVSYNKLTGPVPINGFLKTINPDDLRGNSGLCGGVLPPCSKF 630
Query: 655 RSFPLCRQTCTRKRLNLMWVV-VASVFLLLVGAIL---FLKQWSRKGKSLIGNDETMSSS 714 + + KR+ W++ +ASV L + I+ K+W G DET S Sbjct: 631 QRATSSHSSLHGKRIVAGWLIGIASVLALGILTIVTRTLYKKWYSNG---FCGDETASKG 690
Query: 715 LCSYDVKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGLS-NGEIVAVKKLWSRKTK 774 + + +FHR+ F +IL + + N++G G +G VY+ +S + ++AVKKLW R Sbjct: 691 EWPWRLMAFHRLGFTASDILACIKESNMIGMGATGIVYKAEMSRSSTVLAVKKLW-RSAA 750
Query: 775 DKVSEDQVFPDKELETEVETLGNIRHKNIVKLYCYLSSLDCSLLVYEYMPNGNLWDALHK 834 D ED D EV LG +RH+NIV+L +L + ++VYE+M NGNL DA+H Sbjct: 751 D--IEDGTTGD--FVGEVNLLGKLRHRNIVRLLGFLYNDKNMMIVYEFMLNGNLGDAIHG 810
Query: 36 LTRPVMGFQSFYLSCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSGKALSYWNSQSYCNY 95 L P F S L LSLL+ S S S F K ++G+ + W C++ Sbjct: 18 LLLPFFAFNSLALKFSPQLLSLLSLKTSLSGPPSA-FQDWKVPVNGQNDAVW-----CSW 77
Query: 96 TGVTC-NIQNQVTKV------------------------NISGWSLKGSLPSNLCSYLPE 155 +GV C N+ QV + N+SG SL+GS P+++ L + Sbjct: 78 SGVVCDNVTAQVISLDLSHRNLSGRIPIQIRYLSSLLYLNLSGNSLEGSFPTSIFD-LTK 137
Query: 156 LRVLDISNNSIQGTFPDGIINCSFLEVLNMSSLNLSGKLPN-FSRMKSLRALDLSYNLFD 215 L LDIS NS +FP GI FL+V N S N G LP+ SR++ L L+ + F+ Sbjct: 138 LTTLDISRNSFDSSFPPGISKLKFLKVFNAFSNNFEGLLPSDVSRLRFLEELNFGGSYFE 197
Query: 216 GDFPMSIMNLTNIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNM 275 G+ P + L ++ ++ N+ +LP + LT ++ + + G I + Sbjct: 198 GEIPAAYGGLQRLKFIHLA--GNVLGGKLPPRLGLLTELQHMEIGYNHFNGNIPSEFALL 257
Query: 276 SSLVDLELSGNYLRGWIPHELGRLKNLKSLMLYYNELTGTIPEELGNLTELTDLDMSVNK 335 S+L ++S L G +P ELG L NL++L L+ N TG IPE NL L LD S N+ Sbjct: 258 SNLKYFDVSNCSLSGSLPQELGNLSNLETLFLFQNGFTGEIPESYSNLKSLKLLDFSSNQ 317
Query: 336 LTGRIPDSICRLPKLRGLQIYNNSLTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKS 395 L+G IP L L L + +N+L+GE+P +G L+ L +++N TG +P LG + Sbjct: 318 LSGSIPSGFSTLKNLTWLSLISNNLSGEVPEGIGELPELTTLFLWNNNFTGVLPHKLGSN 377
Query: 456 LKGSVPQGLFGLPHVAVIDLAFNQFTGKI------SPLIGY------------------A 515 L G++P G L ++ +DL+ N+FT +I +P++ Y A Sbjct: 438 LNGTIPIGFGSLRNLTFVDLSNNRFTDQIPADFATAPVLQYLNLSTNFFHRKLPENIWKA 497
Query: 516 KNLSEFLAQSNKLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNK 575 NL F A + L G +P + G S +++L N L+G IP +IG+ +KL L L N Sbjct: 498 PNLQIFSASFSNLIGEIPNYV-GCKSFYRIELQGNSLNGTIPWDIGHCEKLLCLNLSQNH 557
Query: 576 LNSSIPDSLSELKSLNLLDLSSNLLTGNLPHSL-SELIPNSVNFSNNHLYGPIPLSLIKE 635 LN IP +S L S+ +DLS NLLTG +P S + N S N L GPIP Sbjct: 558 LNGIIPWEISTLPSIADVDLSHNLLTGTIPSDFGSSKTITTFNVSYNQLIGPIPSGSFAH 617
Query: 636 GLEDSFLENPGLCVTTYTYSSDRSFPLCRQTCTRKRLN---------------------L 695 F N GLC L + C R N + Sbjct: 618 LNPSFFSSNEGLC-----------GDLVGKPCNSDRFNAGNADIDGHHKEERPKKTAGAI 677
Query: 43 FQSFYLSCFIIFLSLLNSVQS----TSNQQSQYFTLMKNSLSGKALSYWN----SQSYCN 102 F F+ CF NS QS +SNQQ Q+F LMKNSL G ALS WN +YCN Sbjct: 9 FVLFFFFCF-------NSNQSWGLMSSNQQPQFFKLMKNSLFGDALSTWNVYDVGTNYCN 68
Query: 103 YTGVTCNIQNQVTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQ--GTFPDGIINC 162 +TGV C+ Q VT +++SG SL G P +CSY P LRVL +S+N + +F + I NC Sbjct: 69 FTGVRCDGQGLVTDLDLSGLSLSGIFPDGVCSYFPNLRVLRLSHNHLNKSSSFLNTIPNC 128
Query: 163 SFLEVLNMSSLNLSGKLPNFSRMKSLRALDLSYNLFDGDFPMSIMNLTNIEVVNFNENSN 222 S L LNMSS+ L G LP+FS+MKSLR +D+S+N F G FP+SI NLT++E +NFNEN Sbjct: 129 SLLRDLNMSSVYLKGTLPDFSQMKSLRVIDMSWNHFTGSFPLSIFNLTDLEYLNFNENPE 188
Query: 223 LNRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGR 282 L+ W LP+++++LT++ ++L T L G I SIGN++SLVDLELSGN+L G IP E+G Sbjct: 189 LDLWTLPDSVSKLTKLTHMLLMTCMLHGNIPRSIGNLTSLVDLELSGNFLSGEIPKEIGN 248
Query: 283 LKNLKSLMLYYN-ELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYN 342 L NL+ L LYYN LTG+IPEE+GNL LTD+D+SV++LTG IPDSIC LP LR LQ+YN Sbjct: 249 LSNLRQLELYYNYHLTGSIPEEIGNLKNLTDIDISVSRLTGSIPDSICSLPNLRVLQLYN 308
Query: 343 NSLTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQIC 402 NSLTGEIP LGNS TL LS+Y N+LTGE+P NLG SS M LD+SEN+L+G LP +C Sbjct: 309 NSLTGEIPKSLGNSKTLKILSLYDNYLTGELPPNLGSSSPMIALDVSENRLSGPLPAHVC 368
Query: 403 NGGKLVYFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAF 462 GKL+YFLVL N FTG IPET+ C +L+RFRV++N+L G++PQG+ LPHV++IDLA+ Sbjct: 369 KSGKLLYFLVLQNRFTGSIPETYGSCKTLIRFRVASNRLVGTIPQGVMSLPHVSIIDLAY 428
Query: 463 NQFTGKISPLIGYAKNLSEFLAQSNKLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIG 522 N +G I IG A NLSE QSN++SG +P E+S + +LVK+DLSNN LSGPIPSE+G Sbjct: 429 NSLSGPIPNAIGNAWNLSELFMQSNRISGVIPHELSHSTNLVKLDLSNNQLSGPIPSEVG 488
Query: 823 PSIVHRDIKSSNILLDVDFQPKVADFGVAKVLQAMSGNESSNTVIAGTYGYMDPDYANTS 882 P I+HRDIKS+NILLDV++QPKVADFG+AKVLQA G +S+ TV+AGTYGY+ P+YA +S Sbjct: 789 PPIIHRDIKSTNILLDVNYQPKVADFGIAKVLQA-RGKDSTTTVMAGTYGYLAPEYAYSS 848
Query: 883 KATTKCDVYSFGVVLMELVTGKKPVEAEFGENKNIINWVSTKVETKQGAMEVLDKHVSGS 942 KAT KCDVYSFGVVLMEL+TGKKPV++ FGENKNI+NWVSTK++TK+G +E LDK +S S Sbjct: 849 KATIKCDVYSFGVVLMELITGKKPVDSCFGENKNIVNWVSTKIDTKEGLIETLDKRLSES 908
Query: 943 FRDDMLQVICMAIRCTARAPVPRPTMNEIVQFLGEIEP 969 + DM+ + +AIRCT+R P RPTMNE+VQ L + P Sbjct: 909 SKADMINALRVAIRCTSRTPTIRPTMNEVVQLLIDATP 938
Query: 49 SCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSGKALSYWNSQSY------CNYTGVTCNI 108 S F++F SL + V S+ Q +K+S + L+ ++S C++ GVTCN Sbjct: 15 STFLVF-SLFSVV---SSDDLQVLLKLKSSFADSNLAVFDSWKLNSGIGPCSFIGVTCNS 74
Query: 109 QNQVTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSS 168 + VT++++S L G+ P + + L L + NS+ G P + NC+ L+ L++ + Sbjct: 75 RGNVTEIDLSRRGLSGNFPFDSVCEIQSLEKLSLGFNSLSGIIPSDLKNCTSLKYLDLGN 134
Query: 169 LNLSGKLPNFSRMKSLRALDLSYNLFDGDFPM-SIMNLTNIEVVNFNENSNLNRWELPEN 228 SG P FS + L+ L L+ + F G FP S+ N T++ V++ +N + P Sbjct: 135 NLFSGAFPEFSSLNQLQFLYLNNSAFSGVFPWKSLRNATSLVVLSLGDNPFDATADFPVE 194
Query: 229 ITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLKSLML 288 + L ++ L LS + G I P+IG+++ L +LE+S + L G IP E+ +L NL L L Sbjct: 195 VVSLKKLSWLYLSNCSIAGKIPPAIGDLTELRNLEISDSGLTGEIPSEISKLTNLWQLEL 254
Query: 289 YYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYNNSLTGEIPSV 348 Y N LTG +P GNL LT LD S N L G + + + L L LQ++ N +GEIP Sbjct: 255 YNNSLTGKLPTGFGNLKNLTYLDASTNLLQGDLSE-LRSLTNLVSLQMFENEFSGEIPLE 314
Query: 349 LGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLVYFLV 408 G L LS+Y+N LTG +P+ LG + +D SEN LTG +PP +C GK+ L+ Sbjct: 315 FGEFKDLVNLSLYTNKLTGSLPQGLGSLADFDFIDASENLLTGPIPPDMCKNGKMKALLL 374
Query: 409 LSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGKISPL 468 L N TG IPE++A C +L RFRVS N L G+VP GL+GLP + +ID+ N F G I+ Sbjct: 375 LQNNLTGSIPESYANCLTLQRFRVSENNLNGTVPAGLWGLPKLEIIDIEMNNFEGPITAD 434
Query: 469 IGYAKNLSEFLAQSNKLSGALPPEISGAVSLVKVDLSNNLLSGPIPSEIGNLKKLNLLLL 528 I K L NKLS LP EI SL KV+L+NN +G IPS IG LK L+ L + Sbjct: 435 IKNGKMLGALYLGFNKLSDELPEEIGDTESLTKVELNNNRFTGKIPSSIGKLKGLSSLKM 494
Query: 529 RNNKLNSSIPDS------------------------LSELKSLNLLDLSSNLLTGNLPHS 588 ++N + IPDS L L +LN L+LS N L+G +P S Sbjct: 495 QSNGFSGEIPDSIGSCSMLSDVNMAQNSISGEIPHTLGSLPTLNALNLSDNKLSGRIPES 554
Query: 589 LSELIPNSVNFSNNHLYGPIPLSLIKEGLEDSFLENPGLCVTTYTYSSDRSFPLCRQTCT 648 LS L + ++ SNN L G IPLSL SF NPGLC TT +SF C Sbjct: 555 LSSLRLSLLDLSNNRLSGRIPLSL--SSYNGSFNGNPGLCSTTI-----KSFNRCINPSR 614
Query: 709 RISFNQREILEAMVDKNIVGHGGSGTVYRIGLSNGEIVAVKKLWSRKTKDKVSE------ 768 ++SF + +I++++ ++N++G GG G VYR+ L +G+ VAVK + T+ S Sbjct: 675 KMSFTEDDIIDSIKEENLIGRGGCGDVYRVVLGDGKEVAVKHIRCSSTQKNFSSAMPILT 734
Query: 769 DQVFPDKELETEVETLGNIRHKNIVKLYCYLSSLDCSLLVYEYMPNGNLWDALHK-EKML 828 ++ KE ETEV+TL +IRH N+VKLYC ++S D SLLVYEY+PNG+LWD LH +K Sbjct: 735 EREGRSKEFETEVQTLSSIRHLNVVKLYCSITSDDSSLLVYEYLPNGSLWDMLHSCKKSN 794
Query: 829 LDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDIKSSNILLDVDFQPKVADFGVAKVLQAM 888 L W TR+ IALG A+GL YLHH ++HRD+KSSNILLD +P++ADFG+AK+LQA Sbjct: 795 LGWETRYDIALGAAKGLEYLHHGYERPVIHRDVKSSNILLDEFLKPRIADFGLAKILQAS 854
Query: 889 SGNESSNTVIAGTYGYMDP-DYANTSKATTKCDVYSFGVVLMELVTGKKPVEAEFGENKN 948 +G S V+AGTYGY+ P +Y SK T KCDVYSFGVVLMELVTGKKP+EAEFGE+K+ Sbjct: 855 NGGPESTHVVAGTYGYIAPAEYGYASKVTEKCDVYSFGVVLMELVTGKKPIEAEFGESKD 914
Query: 51 FIIFLSLLNSVQSTSNQQSQYFTLMKNSLSG--KALSYWNSQ--SYCNYTGVTCNIQ-NQ 110 +++FL LL + NQ +K SL LS WNS S C ++GV+C + Sbjct: 2 YLLFLFLLFPTVFSLNQDGFILQQVKLSLDDPDSYLSSWNSNDASPCRWSGVSCAGDFSS 61
Query: 111 VTKVNISGWSLKGSLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVLNMSSLNL 170 VT V++S +L G PS +C L L L + NNSI T P I C L+ L++S L Sbjct: 62 VTSVDLSSANLAGPFPSVICR-LSNLAHLSLYNNSINSTLPLNIAACKSLQTLDLSQNLL 121
Query: 171 SGKLP-------------------------NFSRMKSLRALDLSYNLFDGDFPMSIMNLT 230 +G+LP +F + ++L L L YNL DG P + N++ Sbjct: 122 TGELPQTLADIPTLVHLDLTGNNFSGDIPASFGKFENLEVLSLVYNLLDGTIPPFLGNIS 181
Query: 231 NIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGN 290 ++++N + N + +P LT + + L+ L G I S+G +S LVDL+L+ N Sbjct: 182 TLKMLNLSYNP-FSPSRIPPEFGNLTNLEVMWLTECHLVGQIPDSLGQLSKLVDLDLALN 241
Query: 291 YLRGWIPHELGRLKNLKSLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICR 350 L G IP LG L N+ + LY N LTG IP ELGNL L LD S+N+LTG+IPD +CR Sbjct: 242 DLVGHIPPSLGGLTNVVQIELYNNSLTGEIPPELGNLKSLRLLDASMNQLTGKIPDELCR 301
Query: 351 LPKLRGLQIYNNSLTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSEN 410 +P L L +Y N+L GE+P+ + S L + I+ N LTG +PK+LG +S + LD+SEN Sbjct: 302 VP-LESLNLYENNLEGELPASIALSPNLYEIRIFGNRLTGGLPKDLGLNSPLRWLDVSEN 361
Query: 411 KLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFG 470 + +G LP +C G+L L++ N F+G IPE+ A C SL R R++ N+ GSVP G +G Sbjct: 362 EFSGDLPADLCAKGELEELLIIHNSFSGVIPESLADCRSLTRIRLAYNRFSGSVPTGFWG 421
Query: 471 LPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSNKLSGALPPEISGAVSLVKVDLSNN 530 LPHV +++L N F+G+IS IG A NLS + +N+ +G+LP EI +L ++ S N Sbjct: 422 LPHVNLLELVNNSFSGEISKSIGGASNLSLLILSNNEFTGSLPEEIGSLDNLNQLSASGN 481
Query: 531 LLSGPIPS------EIGNL------------------KKLNLLLLRNNKLNSSIPDSLSE 590 SG +P E+G L KKLN L L +N+ IPD + Sbjct: 482 KFSGSLPDSLMSLGELGTLDLHGNQFSGELTSGIKSWKKLNELNLADNEFTGKIPDEIGS 541
Query: 591 LKSLNLLDLSSNLLTGNLPHSLSELIPNSVNFSNNHLYGPIPLSLIKEGLEDSFLENPGL 650 L LN LDLS N+ +G +P SL L N +N S N L G +P SL K+ ++SF+ NPGL Sbjct: 542 LSVLNYLDLSGNMFSGKIPVSLQSLKLNQLNLSYNRLSGDLPPSLAKDMYKNSFIGNPGL 601
Query: 651 CVTTYTYSSDRSFPLCRQTCTRKRLNLMWVVVASVFLLLVGAILFLKQWSRKGKSLIGND 710 C LC K+ +W ++ S+F+L +L W Sbjct: 602 CGDIK--------GLCGSENEAKKRGYVW-LLRSIFVLAAMVLLAGVAWFYFKYRTFKKA 661
Query: 711 ETMSSSLCSYDVKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGLSNGEIVAVKKLW 770 M S + + SFH++ F++ EILE++ + N++G G SG VY++ L+NGE VAVK+LW Sbjct: 662 RAMERS--KWTLMSFHKLGFSEHEILESLDEDNVIGAGASGKVYKVVLTNGETVAVKRLW 721
Query: 771 S---RKTKDKVSEDQVFP---DKELETEVETLGNIRHKNIVKLYCYLSSLDCSLLVYEYM 830 + ++T D E P D+ E EVETLG IRHKNIVKL+C S+ DC LLVYEYM Sbjct: 722 TGSVKETGDCDPEKGYKPGVQDEAFEAEVETLGKIRHKNIVKLWCCCSTRDCKLLVYEYM 781
Query: 831 PNGNLWDALHKEK-MLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDIKSSNILLDVDF 890 PNG+L D LH K +L W TR +I L A+GL+YLHHD +P IVHRDIKS+NIL+D D+ Sbjct: 782 PNGSLGDLLHSSKGGMLGWQTRFKIILDAAEGLSYLHHDSVPPIVHRDIKSNNILIDGDY 841
Query: 891 QPKVADFGVAKVLQAMSGNESSNTVIAGTYGYMDPDYANTSKATTKCDVYSFGVVLMELV 950 +VADFGVAK + S +VIAG+ GY+ P+YA T + K D+YSFGVV++E+V Sbjct: 842 GARVADFGVAKAVDLTGKAPKSMSVIAGSCGYIAPEYAYTLRVNEKSDIYSFGVVILEIV 901
Query: 951 TGKKPVEAEFGENKNIINWVSTKVETKQGAMEVLDKHVSGSFRDDMLQVICMAIRCTARA 967 T K+PV+ E GE K+++ WV + ++ K G V+D + F++++ +++ + + CT+ Sbjct: 902 TRKRPVDPELGE-KDLVKWVCSTLDQK-GIEHVIDPKLDSCFKEEISKILNVGLLCTSPL 961
Query: 48 LSCFIIFLSLLNSVQSTSNQQSQYFTLMKNSLSG-----KALSYW---NSQSYCNYTGVT 107 L C I+ L L +S S +Q T+++ + G ++LS W N + C + GV+ Sbjct: 2 LYCLILLLCL-SSTYLPSLSLNQDATILRQAKLGLSDPAQSLSSWSDNNDVTPCKWLGVS 61
Query: 108 CNIQNQVTKVNISGWSLKGSLPSNLC------------------------SYLPELRVLD 167 C+ + V V++S + L G PS LC L LD Sbjct: 62 CDATSNVVSVDLSSFMLVGPFPSILCHLPSLHSLSLYNNSINGSLSADDFDTCHNLISLD 121
Query: 168 ISNNSIQGTFPDGI-INCSFLEVLNMSSLNLSGKLPN-FSRMKSLRALDLSYNLFDGDFP 227 +S N + G+ P + N L+ L +S NLS +P+ F + L +L+L+ N G P Sbjct: 122 LSENLLVGSIPKSLPFNLPNLKFLEISGNNLSDTIPSSFGEFRKLESLNLAGNFLSGTIP 181
Query: 228 MSIMNLTNIEVVNFNENSNLNRWELPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLV 287 S+ N+T ++ + N + ++P + LT ++ L L+ L G I PS+ ++SLV Sbjct: 182 ASLGNVTTLKELKLAYNL-FSPSQIPSQLGNLTELQVLWLAGCNLVGPIPPSLSRLTSLV 241
Query: 288 DLELSGNYLRGWIPHELGRLKNLKSLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGR 347 +L+L+ N L G IP + +LK ++ + L+ N +G +PE +GN+T L D S+NKLTG+ Sbjct: 242 NLDLTFNQLTGSIPSWITQLKTVEQIELFNNSFSGELPESMGNMTTLKRFDASMNKLTGK 301
Query: 348 IPDSICRLPKLRGLQIYNNSLTGEIPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMT 407 IPD++ L L L ++ N L G +P + S TLS L +++N LTG +P LG +S + Sbjct: 302 IPDNL-NLLNLESLNLFENMLEGPLPESITRSKTLSELKLFNNRLTGVLPSQLGANSPLQ 361
Query: 408 LLDLSENKLTGKLPPQICNGGKLVYFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGS 467 +DLS N+ +G++P +C GKL Y +++ N F+GEI KC SL R R+SNN+L G Sbjct: 362 YVDLSYNRFSGEIPANVCGEGKLEYLILIDNSFSGEISNNLGKCKSLTRVRLSNNKLSGQ 421
Query: 468 VPQGLFGLPHVAVIDLAFNQFTGKISPLIGYAKNLSEFLAQSNKLSGALPPEI------- 527 +P G +GLP +++++L+ N FTG I I AKNLS N+ SG++P EI Sbjct: 422 IPHGFWGLPRLSLLELSDNSFTGSIPKTIIGAKNLSNLRISKNRFSGSIPNEIGSLNGII 481
Query: 528 --SGAVS---------------LVKVDLSNNLLSGPIPSEIGNLKKLNLLLLRNNKLNSS 587 SGA + L ++DLS N LSG IP E+ K LN L L NN L+ Sbjct: 482 EISGAENDFSGEIPESLVKLKQLSRLDLSKNQLSGEIPRELRGWKNLNELNLANNHLSGE 541
Query: 588 IPDSLSELKSLNLLDLSSNLLTGNLPHSLSELIPNSVNFSNNHLYGPIPLSLIKEGLEDS 647 IP + L LN LDLSSN +G +P L L N +N S NHL G IP + Sbjct: 542 IPKEVGILPVLNYLDLSSNQFSGEIPLELQNLKLNVLNLSYNHLSGKIPPLYANKIYAHD 601
Query: 708 WSRKGKSLIGNDETMSSSLCSYDVKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGL 767 RK ++L SS+L + +SFH++ F++ EI + + +KN++G G SG VY++ L Sbjct: 662 -CRKLRAL------KSSTLAASKWRSFHKLHFSEHEIADCLDEKNVIGFGSSGKVYKVEL 721
Query: 768 SNGEIVAVKKLWSRKTK---DKVSEDQVFPDKELETEVETLGNIRHKNIVKLYCYLSSLD 827 GE+VAVKKL ++ K D+ S D + D EVETLG IRHK+IV+L+C SS D Sbjct: 722 RGGEVVAVKKL-NKSVKGGDDEYSSDSLNRD-VFAAEVETLGTIRHKSIVRLWCCCSSGD 781
Query: 828 CSLLVYEYMPNGNLWDALHKEK---MLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDI 887 C LLVYEYMPNG+L D LH ++ ++L WP R +IAL A+GL+YLHHD +P IVHRD+ Sbjct: 782 CKLLVYEYMPNGSLADVLHGDRKGGVVLGWPERLRIALDAAEGLSYLHHDCVPPIVHRDV 841
Query: 888 KSSNILLDVDFQPKVADFGVAKVLQAMSGNESSNTV--IAGTYGYMDPDYANTSKATTKC 947 KSSNILLD D+ KVADFG+AKV Q MSG+++ + IAG+ GY+ P+Y T + K Sbjct: 842 KSSNILLDSDYGAKVADFGIAKVGQ-MSGSKTPEAMSGIAGSCGYIAPEYVYTLRVNEKS 901
Query: 948 DVYSFGVVLMELVTGKKPVEAEFGENKNIINWVSTKVETKQGAMEVLDKHVSGSFRDDML 984 D+YSFGVVL+ELVTGK+P ++E G+ K++ WV T ++ K G V+D + F++++ Sbjct: 902 DIYSFGVVLLELVTGKQPTDSELGD-KDMAKWVCTALD-KCGLEPVIDPKLDLKFKEEIS 961
Query: 52 IIFLSLLNSVQSTSNQQSQYFTLMKNSL----SGKALSYWNSQ-SYCNYTGVTCNIQNQV 111 ++FL L S +S +++ + +K++ S W + S C + G+ CN V Sbjct: 10 LLFLMPLASSRSNHSEEVENLLKLKSTFGETKSDDVFKTWTHRNSACEFAGIVCNSDGNV 69
Query: 112 TKVNISGWSLKG--------SLPSNLCSYLPELRVLDISNNSIQGTFPDGIINCSFLEVL 171 ++N+ SL LP + L L L + NNS++G + C+ L L Sbjct: 70 VEINLGSRSLINRDDDGRFTDLPFDSICDLKLLEKLVLGNNSLRGQIGTNLGKCNRLRYL 129
Query: 172 NMSSLNLSGKLPNFSRMKSLRALDLSYNLFDGDFPMS-IMNLTNIEVVNFNENSNLNRWE 231 ++ N SG+ P ++ L L L+ + G FP S + +L + ++ +N Sbjct: 130 DLGINNFSGEFPAIDSLQLLEFLSLNASGISGIFPWSSLKDLKRLSFLSVGDN-RFGSHP 189
Query: 232 LPENITRLTRIRTLVLSTTKLQGLILPSIGNMSSLVDLELSGNYLRGWIPHELGRLKNLK 291 P I LT ++ + LS + + G I I N+ L +LELS N + G IP E+ +LKNL+ Sbjct: 190 FPREILNLTALQWVYLSNSSITGKIPEGIKNLVRLQNLELSDNQISGEIPKEIVQLKNLR 249
Query: 292 SLMLYYNELTGTIPEELGNLTELTDLDMSVNKLTGRIPDSICRLPKLRGLQIYNNSLTGE 351 L +Y N+LTG +P NLT L + D S N L G + + + L L L ++ N LTGE Sbjct: 250 QLEIYSNDLTGKLPLGFRNLTNLRNFDASNNSLEGDLSE-LRFLKNLVSLGMFENRLTGE 309
Query: 352 IPSVLGNSNTLSFLSIYSNFLTGEVPKNLGKSSTMTLLDLSENKLTGKLPPQICNGGKLV 411 IP G+ +L+ LS+Y N LTG++P+ LG + +D+SEN L G++PP +C G + Sbjct: 310 IPKEFGDFKSLAALSLYRNQLTGKLPRRLGSWTAFKYIDVSENFLEGQIPPYMCKKGVMT 369
Query: 412 YFLVLSNMFTGEIPETFAKCTSLVRFRVSNNQLKGSVPQGLFGLPHVAVIDLAFNQFTGK 471 + L+L N FTG+ PE++AKC +L+R RVSNN L G +P G++GLP++ +DLA N F G Sbjct: 370 HLLMLQNRFTGQFPESYAKCKTLIRLRVSNNSLSGMIPSGIWGLPNLQFLDLASNYFEGN 429
Query: 532 LLLL------------------------RNNKLNSSIPDSLSELKSLNLLDLSSNLLTGN 591 L+L N L+ IP+SL LK LN L+LS N L+G Sbjct: 490 SLILDQNNLSGAIPKSLGLCTSLVDLNFAGNSLSEEIPESLGSLKLLNSLNLSGNKLSGM 549
Query: 592 LPHSLSELIPNSVNFSNNHLYGPIPLSLIKEGLEDSFLENPGLCVTTYTYSSDRSFPLCR 651 +P LS L + ++ SNN L G +P SL+ SF N GLC + Y R PL + Sbjct: 550 IPVGLSALKLSLLDLSNNQLTGSVPESLV----SGSFEGNSGLCSSKIRYL--RPCPLGK 609
Query: 652 QTCTRKRLNL----MWVVVASVFLL--LVGAILFLKQWSRKGKSLIGNDETMSSSLCSYD 711 KR +L M +VA++ L L ++F + + K++ ++ + Sbjct: 610 PHSQGKRKHLSKVDMCFIVAAILALFFLFSYVIFKIRRDKLNKTVQKKND--------WQ 669
Query: 712 VKSFHRISFNQREILEAMVDKNIVGHGGSGTVYRIGLSNGEIVAVKKLWSRKTKDKV--S 771 V SF ++FN+ EI++ + +NI+G GG G VY++ L +GE +AVK +W ++ + S Sbjct: 670 VSSFRLLNFNEMEIIDEIKSENIIGRGGQGNVYKVSLRSGETLAVKHIWCPESSHESFRS 729
Query: 772 EDQVFPD-------KELETEVETLGNIRHKNIVKLYCYLSSLDCSLLVYEYMPNGNLWDA 831 + D E E EV TL NI+H N+VKL+C ++ D LLVYEYMPNG+LW+ Sbjct: 730 STAMLSDGNNRSNNGEFEAEVATLSNIKHINVVKLFCSITCEDSKLLVYEYMPNGSLWEQ 789
Query: 832 LHKEK--MLLDWPTRHQIALGVAQGLAYLHHDLLPSIVHRDIKSSNILLDVDFQPKVADF 891 LH+ + + W R +ALG A+GL YLHH L ++HRD+KSSNILLD +++P++ADF Sbjct: 790 LHERRGEQEIGWRVRQALALGAAKGLEYLHHGLDRPVIHRDVKSSNILLDEEWRPRIADF 849
Query: 892 GVAKVLQAMS-GNESSNTVIAGTYGYMDPDYANTSKATTKCDVYSFGVVLMELVTGKKPV 951 G+AK++QA S + S ++ GT GY+ P+YA T+K K DVYSFGVVLMELVTGKKP+ Sbjct: 850 GLAKIIQADSVQRDFSAPLVKGTLGYIAPEYAYTTKVNEKSDVYSFGVVLMELVTGKKPL 909
